Literature DB >> 12467768

Neutrophil elastase-mediated killing of bacteria: lessons from targeted mutagenesis.

Abderrazzaq Belaaouaj1.   

Abstract

Engineering of mice deficient in neutrophil elastase (NE) has allowed us to demonstrate the role of this protease in host defense against bacteria and to begin to understand its killing mechanism. Strategies to inhibit NE because of its involvement in tissue-destructive diseases should be reconsidered, while preserving its beneficial properties.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12467768     DOI： 10.1016/s1286-4579(02)01654-4

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  23 in total

1.  SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice.

Authors:  Fabienne Gally; Y Peter Di; Sean K Smith; Maisha N Minor; Yang Liu; Donna L Bratton; S Courtney Frasch; Nicole M Michels; Stephanie R Case; Hong Wei Chu
Journal:  Am J Pathol       Date:  2011-05       Impact factor: 4.307

2.  NSP4, an elastase-related protease in human neutrophils with arginine specificity.

Authors:  Natascha C Perera; Oliver Schilling; Heike Kittel; Walter Back; Elisabeth Kremmer; Dieter E Jenne
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-02       Impact factor: 11.205

3.  Miropin, a novel bacterial serpin from the periodontopathogen Tannerella forsythia, inhibits a broad range of proteases by using different peptide bonds within the reactive center loop.

Authors:  Miroslaw Ksiazek; Danuta Mizgalska; Jan J Enghild; Carsten Scavenius; Ida B Thogersen; Jan Potempa
Journal:  J Biol Chem       Date:  2014-11-11       Impact factor: 5.157

4.  Neutrophil elastase, an innate immunity effector molecule, represses flagellin transcription in Pseudomonas aeruginosa.

Authors:  Avinash Sonawane; Jeevan Jyot; Russell During; Reuben Ramphal
Journal:  Infect Immun       Date:  2006-09-18       Impact factor: 3.441

5.  Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions.

Authors:  Tae Kwon Kim; Lucas Tirloni; Zeljko Radulovic; Lauren Lewis; Mariam Bakshi; Creston Hill; Itabajara da Silva Vaz; Carlos Logullo; Carlos Termignoni; Albert Mulenga
Journal:  Int J Parasitol       Date:  2015-05-05       Impact factor: 3.981

6.  Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases.

Authors:  Timofey Kalupov; Michèle Brillard-Bourdet; Sébastien Dadé; Hélène Serrano; Julien Wartelle; Nicolas Guyot; Luiz Juliano; Thierry Moreau; Azzaq Belaaouaj; Francis Gauthier
Journal:  J Biol Chem       Date:  2009-10-15       Impact factor: 5.157

7.  Short Palate, Lung, and Nasal Epithelial Clone 1 Has Antimicrobial and Antibiofilm Activities against the Burkholderia cepacia Complex.

Authors:  Saira Ahmad; Jean Tyrrell; William G Walton; Ashutosh Tripathy; Matthew R Redinbo; Robert Tarran
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

8.  The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase.

Authors:  Christopher T Eggers; Iain A Murray; Valerie A Delmar; Anthony G Day; Charles S Craik
Journal:  Biochem J       Date:  2004-04-01       Impact factor: 3.857

9.  Proteases, neutrophils, and periodontitis: the NET effect.

Authors:  William M Nauseef
Journal:  J Clin Invest       Date:  2014-09-17       Impact factor: 14.808

10.  Methionine sulfoxide reductases protect against oxidative stress in Staphylococcus aureus encountering exogenous oxidants and human neutrophils.

Authors:  Yun Yun Pang; Jamie Schwartz; Sarah Bloomberg; Jeffrey M Boyd; Alexander R Horswill; William M Nauseef
Journal:  J Innate Immun       Date:  2013-11-15       Impact factor: 7.349
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.