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Literature DB >> 12467621

Hepatoprotective pyrrole derivatives of Lycium chinense fruits.

Young-Won Chin¹, Song-Won Lim, Seok-Ho Kim, Dong-Yun Shin, Young-Ger Suh, Yang-Bae Kim, Young Choong Kim, Jinwoong Kim.

Abstract

As a part of our search for hepatoprotective compounds from Lycium chinense fruits, three new pyrrole derivatives (1-3) were isolated. These compounds and a related synthetic methylated compound (4) were evaluated for their biological activity and structure-activity relationship, and compounds 1 and 2 showed hepatoprotective effects comparable to silybin at the concentration of 0.1 microM (64.4 and 65.8%, respectively).

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Year: 2003 PMID： 12467621 DOI： 10.1016/s0960-894x(02)00846-6

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

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Cited

10 in total

1. Discrimination of Lycium chinense and Lycium barbarum by taste pattern and betaine analysis.

Authors: Hye Won Lee; Young Hwa Kim; Yun Hee Kim; Gwan Ho Lee; Mi Young Lee
Journal: Int J Clin Exp Med Date: 2014-08-15

2. Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark of Lycium chinense (Cortex Lycii) against gastric ulcer in mice.

Authors: Hongxia Chen; Opeyemi J Olatunji; Yifeng Zhou
Journal: J Nat Med Date: 2016-03-14 Impact factor: 2.343

3. Pyrrole alkaloids with potential cancer chemopreventive activity isolated from a goji berry-contaminated commercial sample of African mango.

Authors: Jie Li; Li Pan; C Benjamin Naman; Ye Deng; Heebyung Chai; William J Keller; A Douglas Kinghorn
Journal: J Agric Food Chem Date: 2014-05-27 Impact factor: 5.279

4. Family-level stereoselective synthesis and biological evaluation of pyrrolomorpholine spiroketal natural product antioxidants.

Authors: Alyssa L Verano; Derek S Tan
Journal: Chem Sci Date: 2017-03-15 Impact factor: 9.825

Review 5. Systematic Review of Chemical Constituents in the Genus Lycium (Solanaceae).

Authors: Dan Qian; Yaxing Zhao; Guang Yang; Luqi Huang
Journal: Molecules Date: 2017-06-08 Impact factor: 4.411

6. Phenolic Acid Derivatives, Flavonoids and Other Bioactive Compounds from the Leaves of Cardiocrinum cordatum (Thunb.) Makino (Liliaceae).

Authors: Kengo Hori; Takashi Watanabe; Hari Prasad Devkota
Journal: Plants (Basel) Date: 2021-02-07

Hepatoprotective pyrrole derivatives of Lycium chinense fruits.

1. Discrimination of Lycium chinense and Lycium barbarum by taste pattern and betaine analysis.

2. Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark of Lycium chinense (Cortex Lycii) against gastric ulcer in mice.

3. Pyrrole alkaloids with potential cancer chemopreventive activity isolated from a goji berry-contaminated commercial sample of African mango.

4. Family-level stereoselective synthesis and biological evaluation of pyrrolomorpholine spiroketal natural product antioxidants.

Review 5. Systematic Review of Chemical Constituents in the Genus Lycium (Solanaceae).

6. Phenolic Acid Derivatives, Flavonoids and Other Bioactive Compounds from the Leaves of Cardiocrinum cordatum (Thunb.) Makino (Liliaceae).

7. Discrimination of Lycium chinense and L. barbarum Based on Metabolite Analysis and Hepatoprotective Activity.

Review 8. Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup.

9. Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity.

10. Identification of a Novel Pyrrole Alkaloid from the Edible Mushroom Basidiomycetes-X (Echigoshirayukidake).