Literature DB >> 12467607

Caged RNase: photoactivation of the enzyme from perfect off-state by site-specific incorporation of 2-nitrobenzyl moiety.

Takashi Hiraoka1, Itaru Hamachi.   

Abstract

Photo-triggered activation of semisynthetic Ribonuclease S' from a perfect off-state was successfully carried out by incorporation of photo-labile caged moiety into a proximity to the active site.

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Year:  2003        PMID： 12467607     DOI： 10.1016/s0960-894x(02)00825-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor.

Authors:  Jiří Schimer; Marcela Pávová; Maria Anders; Petr Pachl; Pavel Šácha; Petr Cígler; Jan Weber; Pavel Majer; Pavlína Řezáčová; Hans-Georg Kräusslich; Barbara Müller; Jan Konvalinka
Journal:  Nat Commun       Date:  2015-03-09       Impact factor: 14.919

Review 2.  Stimulus-Responsive Regulation of Enzyme Activity for One-Step and Multi-Step Syntheses.

Authors:  Christiane Claaßen; Tim Gerlach; Dörte Rother
Journal:  Adv Synth Catal       Date:  2019-04-15       Impact factor: 5.837
  2 in total

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