Literature DB >> 12466485

The first hydrophobic domain of the hepatitis C virus E1 protein is important for interaction with the capsid protein.

Hsin-Chieh Ma1, Cheng-Hung Ke1, Tsai-Yuan Hsieh2, Shih-Yen Lo3,1.   

Abstract

The interaction between the hepatitis C virus capsid protein and the envelope protein E1 has been demonstrated previously in vivo. To determine the binding region of the E1 protein with the capsid protein, this interaction was characterized in vitro. This study shows that the interaction between these proteins should occur in the endoplasmic reticulum membrane rather than in the cytosol and that the first hydrophobic domain of the E1 protein (aa 261-291) is important for the interaction with the capsid protein.

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Year:  2002        PMID： 12466485     DOI： 10.1099/0022-1317-83-12-3085

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  16 in total

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Journal:  J Virol       Date:  2006-09-13       Impact factor: 5.103

Review 3.  Molecular biology of hepatitis C virus.

Authors:  Tetsuro Suzuki; Hideki Aizaki; Kyoko Murakami; Ikuo Shoji; Takaji Wakita
Journal:  J Gastroenterol       Date:  2007-06-29       Impact factor: 7.527

4.  Hepatitis C virus NS2 protein contributes to virus particle assembly via opposing epistatic interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.

Authors:  Tung Phan; Rudolf K F Beran; Christopher Peters; Ivo C Lorenz; Brett D Lindenbach
Journal:  J Virol       Date:  2009-06-10       Impact factor: 5.103

5.  Identification of residues in the hepatitis C virus core protein that are critical for capsid assembly in a cell-free system.

Authors:  Kevin C Klein; Sheri R Dellos; Jaisri R Lingappa
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6.  Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening.

Authors:  Jennifer M Pfaff-Kilgore; Edgar Davidson; Kathryn Kadash-Edmondson; Mayda Hernandez; Erin Rosenberg; Ross Chambers; Matteo Castelli; Nicola Clementi; Nicasio Mancini; Justin R Bailey; James E Crowe; Mansun Law; Benjamin J Doranz
Journal:  Cell Rep       Date:  2022-05-24       Impact factor: 9.995

7.  Characterization of hepatitis C virus core protein multimerization and membrane envelopment: revelation of a cascade of core-membrane interactions.

Authors:  Li-Shuang Ai; Yu-Wen Lee; Steve S-L Chen
Journal:  J Virol       Date:  2009-07-15       Impact factor: 5.103

8.  Hepatitis C virus-like particle budding: role of the core protein and importance of its Asp111.

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Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

9.  Coexpression of hepatitis C virus E1 and E2 chimeric envelope glycoproteins displays separable ligand sensitivity and increases pseudotype infectious titer.

Authors:  Keith Meyer; Aster Beyene; Terry L Bowlin; Arnab Basu; Ranjit Ray
Journal:  J Virol       Date:  2004-12       Impact factor: 5.103

10.  Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A.

Authors:  Margarita Zayas; Gang Long; Vanesa Madan; Ralf Bartenschlager
Journal:  PLoS Pathog       Date:  2016-01-04       Impact factor: 6.823
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