Two-view screening and extending the age range: the balance of benefit and risk.

The UK Breast Screening Programme intends to introduce two-view screening on all screening rounds, and also to extend the normal screening age range at its upper end from the present 64 years to 70 years. The implications of these changes for cancer detection:induction ratios and for benefit/risk ratios are discussed. It is shown that both ratios remain much greater than 1.0 at all screening ages. This is also true for younger women, subject to provisos regarding starting ages for annual screening as described in previous papers. The requirements for optimization in a breast screening programme are also discussed. It is suggested that benefit (rather than the benefit/risk ratio) should be maximized provided that benefit exceeds risk.