Literature DB >> 12466054

Protective effects of trilinolein extracted from panax notoginseng against cardiovascular disease.

Paul Chan1, G Neil Thomas, Brian Tomlinson.   

Abstract

Trilinolein is a triacylglycerol purified from a commonly used traditional Chinese medicine Panax notoginseng. Trilinolein has been reported to provide a number of beneficial effects including reducing thrombogenicity and arrhythmias and increasing erythrocyte deformability. Additionally, trilinolein has been reported to be an antioxidant, which can counteract free radical damage associated with atherogenesis, and myocardial damage seen with ischaemia and reperfusion. These pharmacologic effects may explain the perceived benefits derived from treating circulatory disorders with the herb over the centuries.

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Year:  2002        PMID： 12466054

Source DB:  PubMed          Journal:  Acta Pharmacol Sin        ISSN： 1671-4083            Impact factor:   6.150


  25 in total

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Authors:  Deepak Poudyal; Phuong Mai Le; Tia Davis; Anne B Hofseth; Alena Chumanevich; Alexander A Chumanevich; Michael J Wargovich; Mitzi Nagarkatti; Prakash S Nagarkatti; Anthony Windust; Lorne J Hofseth
Journal:  Cancer Prev Res (Phila)       Date:  2012-01-31

2.  An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes.

Authors:  Jinqing Li; Tomonaga Ichikawa; Yu Jin; Lorne J Hofseth; Prakash Nagarkatti; Mitzi Nagarkatti; Anthony Windust; Taixing Cui
Journal:  J Ethnopharmacol       Date:  2010-05-04       Impact factor: 4.360

3.  Platelet P2Y₁₂ receptors are involved in the haemostatic effect of notoginsenoside Ft1, a saponin isolated from Panax notoginseng.

Authors:  B Gao; L Huang; H Liu; H Wu; E Zhang; L Yang; X Wu; Z Wang
Journal:  Br J Pharmacol       Date:  2014-01       Impact factor: 8.739

4.  Inhibitory effect of trilinolein on endothelin-1-induced c-fos gene expression in cultured neonatal rat cardiomyocytes.

Authors:  Hung-Yu Yang; Ju-Chi Liu; Yen-Ling Chen; Cheng-Hsien Chen; Heng Lin; Jia-Wei Lin; Wen-Ta Chiu; Jin-Jer Chen; Tzu-Hurng Cheng
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-10-22       Impact factor: 3.000

5.  Inhibition of Arterial Myogenic Responses by a Mixed Aqueous Extract of Salvia Miltiorrhiza and Panax Notoginseng (PASEL) Showing Antihypertensive Effects.

Authors:  Eun Bok Baek; Hae Young Yoo; Su Jung Park; Young-Shin Chung; Eun-Kyung Hong; Sung Joon Kim
Journal:  Korean J Physiol Pharmacol       Date:  2009-08-31       Impact factor: 2.016

6.  Antioxidative effects of Panax notoginseng saponins in brain cells.

Authors:  Ningna Zhou; Yang Tang; Richard F Keep; Xiaoxia Ma; Jianming Xiang
Journal:  Phytomedicine       Date:  2014-06-07       Impact factor: 5.340

7.  Detection of adulteration of notoginseng root extract with other panax species by quantitative HPLC coupled with PCA.

Authors:  Chong-Zhi Wang; Ming Ni; Shi Sun; Xiao-Li Li; Hui He; Sangeeta R Mehendale; Chun-Su Yuan
Journal:  J Agric Food Chem       Date:  2009-03-25       Impact factor: 5.279

8.  Anti-oxidative effects of the biennial flower of Panax notoginseng against H2O2-induced cytotoxicity in cultured PC12 cells.

Authors:  Roy Chi-Yan Choi; Zhiyong Jiang; Heidi Qun Xie; Anna Wing-Han Cheung; David Tai-Wai Lau; Qiang Fu; Tina Tingxia Dong; Jijun Chen; Zhengtao Wang; Karl Wah-Keung Tsim
Journal:  Chin Med       Date:  2010-10-28       Impact factor: 5.455

9.  Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng.

Authors:  Dong-Hyun Kim
Journal:  J Ginseng Res       Date:  2012-01       Impact factor: 6.060

10.  Evaluation of anti-fatigue activity of total saponins of Radix notoginseng.

Authors:  Xu Yong-xin; Zhang Jian-jun
Journal:  Indian J Med Res       Date:  2013-01       Impact factor: 2.375
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