Literature DB >> 12465998

Emerging concepts in periodontal therapy.

Henry Greenwell1, Nabil F Bissada.   

Abstract

Conventional periodontal therapy consists of mechanical scaling and root planing, and surgical treatment. This is still the mainstay of periodontal treatment. Adjunctive antimicrobial treatments, both systemic and local delivery, are becoming more sophisticated and useful in the treatment of recurrent periodontitis. Also very promising are adjunctive treatments that modulate the host response and decrease levels of destructive pro-inflammatory cytokines or matrix metalloproteinases. Smoking is a major risk factor for periodontitis and has a profound impact on the progression of periodontal bone and attachment loss. In the interest of improved periodontal health patients should be encouraged to stop smoking. Finally bacterial endotoxins that stimulate the release of pro-inflammatory cytokines can have systemic effects and may lead to pre-term, low birthweight babies, and cardiovascular diseases such as atherosclerosis, myocardial infarction and stroke. Health professionals need to be cognisant of the effect dental health can have on systemic diseases and refer for treatment when appropriate to ensure that optimum oral and systemic health is achieved for their patients.

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Year:  2002        PMID: 12465998     DOI: 10.2165/00003495-200262180-00002

Source DB:  PubMed          Journal:  Drugs        ISSN: 0012-6667            Impact factor:   9.546


  32 in total

Review 1.  Mechanisms of connective tissue matrix destruction in periodontitis.

Authors:  J J Reynolds; M C Meikle
Journal:  Periodontol 2000       Date:  1997-06       Impact factor: 7.589

Review 2.  Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease.

Authors:  E Gemmell; R I Marshall; G J Seymour
Journal:  Periodontol 2000       Date:  1997-06       Impact factor: 7.589

3.  Indomethacin or flurbiprofen treatment of periodontitis in beagles: effect on crevicular fluid arachidonic acid metabolites compared with effect on alveolar bone loss.

Authors:  R C Williams; S Offenbacher; M K Jeffcoat; T H Howell; H G Johnson; C M Hall; W J Wechter; P Goldhaber
Journal:  J Periodontal Res       Date:  1988-03       Impact factor: 4.419

4.  The effect of topical delivery of novel bisacylphosphonates in reducing alveolar bone loss in the rat model.

Authors:  A Yaffe; G Golomb; E Breuer; I Binderman
Journal:  J Periodontol       Date:  2000-10       Impact factor: 6.993

5.  Effects of bisphosphonate on matrix metalloproteinase enzymes in human periodontal ligament cells.

Authors:  H Nakaya; G Osawa; N Iwasaki; D L Cochran; K Kamoi; T W Oates
Journal:  J Periodontol       Date:  2000-07       Impact factor: 6.993

6.  Periodontal infection as a possible risk factor for preterm low birth weight.

Authors:  S Offenbacher; V Katz; G Fertik; J Collins; D Boyd; G Maynor; R McKaig; J Beck
Journal:  J Periodontol       Date:  1996-10       Impact factor: 6.993

Review 7.  Periodontal disease and cardiovascular disease.

Authors:  J Beck; R Garcia; G Heiss; P S Vokonas; S Offenbacher
Journal:  J Periodontol       Date:  1996-10       Impact factor: 6.993

8.  Dental disease, fibrinogen and white cell count; links with myocardial infarction?

Authors:  M Kweider; G D Lowe; G D Murray; D F Kinane; D A McGowan
Journal:  Scott Med J       Date:  1993-06       Impact factor: 0.729

Review 9.  Chlorhexidine: is it still the gold standard?

Authors:  C G Jones
Journal:  Periodontol 2000       Date:  1997-10       Impact factor: 7.589

10.  Periodontal assessment of patients undergoing angioplasty for treatment of coronary artery disease.

Authors:  Anca Bazile; Nabil F Bissada; Ravi Nair; Burton P Siegel
Journal:  J Periodontol       Date:  2002-06       Impact factor: 6.993

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  2 in total

1.  Role of anti-infective strategies in the prevention of stroke.

Authors:  Armin J Grau
Journal:  Curr Treat Options Cardiovasc Med       Date:  2005-07

2.  Concurrent release of admixed antimicrobials and salicylic acid from salicylate-based poly(anhydride-esters).

Authors:  Michelle L Johnson; Kathryn E Uhrich
Journal:  J Biomed Mater Res A       Date:  2009-12       Impact factor: 4.396

  2 in total

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