| Literature DB >> 12465932 |
Amos B Smith1, Dongjoo Lee, Christopher M Adams, Marisa C Kozlowski.
Abstract
[reaction: see text] The Evans-Tishchenko reaction provides an efficient and practical solution for the oxidation of aldehydes possessing sensitive electron-rich heteroatoms to the corresponding esters. Careful selection of the sacrificial beta-hydroxy ketone provides considerable subsequent flexibility to access the desired carboxylic acid.Entities:
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Year: 2002 PMID： 12465932 DOI： 10.1021/ol027095p
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005