Huang Jianqi1, He Hong, Sheng Lieping, Gu Genghua. 1. Received from the Department of Oral and Maxillofacial Surgery, The Second Affiliated Hospital of Medical College, Zhe Jiang University, Hang Zhou, China.
Abstract
PURPOSE: We sought to compare calcium alginate film (CAF) with collagen membrane (CM) regarding their effects on guided bone regeneration. MATERIALS AND METHODS: Circular bone defects with 5-mm diameter were created in the region anterior to both mandibular angles in 34 rabbits. The defects on one side were covered with a CAF, and the contralateral side with CM. Healing condition was analyzed with gross, radiographic, electromicroscopic, histologic, and immunohistochemical studies and image pattern analysis system after 1, 2, 4, 6, and 8 weeks. RESULTS: CM absorbed more slowly but collected fewer osteoinductive factors (P <.05) in the early period. CAF induced dense bone formation, whereas CM produced less newly formed bone. CONCLUSION: CAF is more efficacious than CM in guided bone regeneration in this animal model. Copyright 2002 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 60:1449-1454, 2002
PURPOSE: We sought to compare calcium alginate film (CAF) with collagen membrane (CM) regarding their effects on guided bone regeneration. MATERIALS AND METHODS:Circular bone defects with 5-mm diameter were created in the region anterior to both mandibular angles in 34 rabbits. The defects on one side were covered with a CAF, and the contralateral side with CM. Healing condition was analyzed with gross, radiographic, electromicroscopic, histologic, and immunohistochemical studies and image pattern analysis system after 1, 2, 4, 6, and 8 weeks. RESULTS: CM absorbed more slowly but collected fewer osteoinductive factors (P <.05) in the early period. CAF induced dense bone formation, whereas CM produced less newly formed bone. CONCLUSION:CAF is more efficacious than CM in guided bone regeneration in this animal model. Copyright 2002 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 60:1449-1454, 2002
Authors: R Hurteaux; H Benhayoune; F Edwards-Levy; S Bouthors; G Balossier; D Laurent-Maquin Journal: J Mater Sci Mater Med Date: 2005-01 Impact factor: 3.896