Literature DB >> 12464662

Alternative treatment for secretory diarrhea revealed in a new class of CFTR inhibitors.

Qais Al-Awqati1.   

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Year:  2002        PMID: 12464662      PMCID: PMC151641          DOI: 10.1172/JCI17301

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  17 in total

Review 1.  Sodium-coupled chloride transport by epithelial tissues.

Authors:  R A Frizzell; M Field; S G Schultz
Journal:  Am J Physiol       Date:  1979-01

2.  Choleragen activation of solubilized adenylate cyclase: requirement for GTP and protein activator for demonstration of enzymatic activity.

Authors:  J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

3.  Reducing deaths from diarrhoea through oral rehydration therapy.

Authors:  C G Victora; J Bryce; O Fontaine; R Monasch
Journal:  Bull World Health Organ       Date:  2000       Impact factor: 9.408

4.  Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.

Authors:  M Field; L H Graf; W J Laird; P L Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

5.  Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

Authors:  J R Riordan; J M Rommens; B Kerem; N Alon; R Rozmahel; Z Grzelczak; J Zielenski; S Lok; N Plavsic; J L Chou
Journal:  Science       Date:  1989-09-08       Impact factor: 47.728

Review 6.  History of the development of oral rehydration therapy.

Authors:  R M da Cunha Ferreira; R A Cash
Journal:  Clin Ther       Date:  1990       Impact factor: 3.393

7.  The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro.

Authors:  C J Davidow; R L Maser; L A Rome; J P Calvet; J J Grantham
Journal:  Kidney Int       Date:  1996-07       Impact factor: 10.612

Review 8.  Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia.

Authors:  M P Anderson; D N Sheppard; H A Berger; M J Welsh
Journal:  Am J Physiol       Date:  1992-07

Review 9.  CFTR is a conductance regulator as well as a chloride channel.

Authors:  E M Schwiebert; D J Benos; M E Egan; M J Stutts; W B Guggino
Journal:  Physiol Rev       Date:  1999-01       Impact factor: 37.312

Review 10.  Role of CFTR in airway disease.

Authors:  J M Pilewski; R A Frizzell
Journal:  Physiol Rev       Date:  1999-01       Impact factor: 37.312

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  7 in total

1.  Mucosal potassium efflux mediated via Kcnn4 channels provides the driving force for electrogenic anion secretion in colon.

Authors:  N S Nanda Kumar; Satish K Singh; Vazhaikkurichi M Rajendran
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-07-08       Impact factor: 4.052

Review 2.  Drug-induced secretory diarrhea: A role for CFTR.

Authors:  Changsuk Moon; Weiqiang Zhang; Nambirajan Sundaram; Sunitha Yarlagadda; Vadde Sudhakar Reddy; Kavisha Arora; Michael A Helmrath; Anjaparavanda P Naren
Journal:  Pharmacol Res       Date:  2015-09-30       Impact factor: 7.658

Review 3.  Structural mechanisms of CFTR function and dysfunction.

Authors:  Tzyh-Chang Hwang; Jiunn-Tyng Yeh; Jingyao Zhang; Ying-Chun Yu; Han-I Yeh; Samantha Destefano
Journal:  J Gen Physiol       Date:  2018-03-26       Impact factor: 4.086

4.  Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function.

Authors:  Adrian W R Serohijos; Tamás Hegedus; Andrei A Aleksandrov; Lihua He; Liying Cui; Nikolay V Dokholyan; John R Riordan
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-27       Impact factor: 11.205

5.  Convective washout reduces the antidiarrheal efficacy of enterocyte surface-targeted antisecretory drugs.

Authors:  Byung-Ju Jin; Jay R Thiagarajah; A S Verkman
Journal:  J Gen Physiol       Date:  2013-02       Impact factor: 4.086

Review 6.  CFTR channel pharmacology: novel pore blockers identified by high-throughput screening.

Authors:  David N Sheppard
Journal:  J Gen Physiol       Date:  2004-08       Impact factor: 4.086

7.  Effects of Small Molecule Calcium-Activated Chloride Channel Inhibitors on Structure and Function of Accessory Cholera Enterotoxin (Ace) of Vibrio cholerae.

Authors:  Tanaya Chatterjee; Irshad Ali Sheikh; Devlina Chakravarty; Pinak Chakrabarti; Paramita Sarkar; Tultul Saha; Manoj K Chakrabarti; Kazi Mirajul Hoque
Journal:  PLoS One       Date:  2015-11-05       Impact factor: 3.240

  7 in total

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