| Literature DB >> 12461561 |
J Victor Small, Benjamin Geiger, Irina Kaverina, Alexander Bershadsky.
Abstract
Microtubules have long been implicated in the polarization of migrating cells, but how they carry out this role is unclear. Here, we propose that microtubules determine cell polarity by modulating the pattern of adhesions that a cell develops with the underlying matrix, through focal inhibitions of contractility.Mesh：
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Year: 2002 PMID： 12461561 DOI： 10.1038/nrm971
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444