BACKGROUND: Acral lentiginous melanoma (ALM) is a subtype of melanoma initially described only two and half decades ago, but well-recognized by dermatologists today. However, several areas of controversy surround this entity. OBJECTIVE: The primary aims of this article are to review the literature, highlight recent advances, and review some of the ongoing controversies in ALM. METHODS: A review of the English language literature was performed. RESULTS: Controversy continues to surround ALM, particularly in regard to diagnostic histologic and clinical criteria. This leads to difficulties when reviewing studies that evaluate the epidemiology, etiology, and prognosis of ALM. CONCLUSION: Progress in understanding ALM requires the development of standardized diagnostic criteria.
BACKGROUND:Acral lentiginous melanoma (ALM) is a subtype of melanoma initially described only two and half decades ago, but well-recognized by dermatologists today. However, several areas of controversy surround this entity. OBJECTIVE: The primary aims of this article are to review the literature, highlight recent advances, and review some of the ongoing controversies in ALM. METHODS: A review of the English language literature was performed. RESULTS: Controversy continues to surround ALM, particularly in regard to diagnostic histologic and clinical criteria. This leads to difficulties when reviewing studies that evaluate the epidemiology, etiology, and prognosis of ALM. CONCLUSION: Progress in understanding ALM requires the development of standardized diagnostic criteria.
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Authors: Katherine Zukotynski; Jeffrey T Yap; Anita Giobbie-Hurder; Jeffrey Weber; Rene Gonzalez; Thomas F Gajewski; Steven O'Day; Kevin Kim; F Stephen Hodi; Annick D Van den Abbeele Journal: Cancer Imaging Date: 2014-11-12 Impact factor: 3.909
Authors: Rosalyn Jewell; Faye Elliott; Jonathan Laye; Jérémie Nsengimana; John Davies; Christy Walker; Caroline Conway; Angana Mitra; Mark Harland; Martin G Cook; Andy Boon; Sarah Storr; Sabreena Safuan; Stewart G Martin; Karin Jirström; Håkan Olsson; Christian Ingvar; Martin Lauss; Tim Bishop; Göran Jönsson; Julia Newton-Bishop Journal: Pigment Cell Melanoma Res Date: 2014-10-01 Impact factor: 4.693
Authors: Sara S Bernardes; Ingrid Ferreira; David E Elder; Aretha B Nobre; Héctor Martínez-Said; David J Adams; Carla Daniela Robles-Espinoza; Patricia A Possik Journal: J Pathol Clin Res Date: 2021-07-02