Literature DB >> 12460296

Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method.

Jung Bock Lee1, Woo Gil Chung, Ho Kwahck, Kwang Hoon Lee.   

Abstract

BACKGROUND: Acne scarring is a common complication of acne and yet no appropriate and effective single treatment modality has been developed. We suggest a technique consisting of the focal application of higher trichloroacetic acid (TCA) concentrations by pressing hard on the entire depressed area of atrophic acne scars. This technique is called chemical reconstruction of skin scars (CROSS) by the authors.
OBJECTIVE: To evaluate the clinical effects of CROSS on atrophic acne scars in dark-complexioned patients.
METHODS: An analysis was conducted of 65 patients with atrophic acne scars who were treated with CROSS in our hospitals between July 1996 and July 2001. Thirty-three patients were treated with 65% TCA CROSS and 32 patients were treated with 100% TCA CROSS. All patients had Fitzpatrick skin types IV-V.
RESULTS: Patient treatment data indicated that 27 of 33 patients (82%) (the 65% TCA group) and 30 of 32 patients (94%) (the 100% TCA group) experienced a good clinical response. All patients in the 100% TCA group who received five or six courses of treatment showed excellent results. Good satisfaction rates in the 65% and 100% TCA groups were recorded. There were no cases of significant complication.
CONCLUSION: CROSS is a safe and very effective single modality for the treatment of atrophic acne scars with no significant complications.

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Year:  2002        PMID: 12460296     DOI: 10.1046/j.1524-4725.2002.02095.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  26 in total

1.  Treatment of Acne Scars of Skin Types II to V by Sublative Fractional Bipolar Radiofrequency and Bipolar Radiofrequency Combined with Diode Laser.

Authors:  Amy Forman Taub; Cara Beth Garretson
Journal:  J Clin Aesthet Dermatol       Date:  2011-10

2.  Worsening of Acne Scars from Trichloroacetic Acid CROSS Delivered via Micropipette: A Case Report.

Authors:  Jesse J Veenstra; Joseph W Fakhoury; David Ozog
Journal:  J Clin Aesthet Dermatol       Date:  2021-04-01

Review 3.  Effective treatments of atrophic acne scars.

Authors:  Maya Valeska Gozali; Bingrong Zhou
Journal:  J Clin Aesthet Dermatol       Date:  2015-05

4.  Practical evaluation and management of atrophic acne scars: tips for the general dermatologist.

Authors:  Douglas Fife
Journal:  J Clin Aesthet Dermatol       Date:  2011-08

Review 5.  Atrophic acne scarring: a review of treatment options.

Authors:  Meghan T Hession; Emmy M Graber
Journal:  J Clin Aesthet Dermatol       Date:  2015-01

6.  An Assessment of the Efficacy and Safety of CROSS Technique with 100% TCA in the Management of Ice Pick Acne Scars.

Authors:  Deepali Bhardwaj; Niti Khunger
Journal:  J Cutan Aesthet Surg       Date:  2010-05

7.  In vitro cytogenetic assessment of trichloroacetic acid in human peripheral blood lymphocytes.

Authors:  Meenu Varshney; Abhijit Chandra; L K S Chauhan; S K Goel
Journal:  Environ Sci Pollut Res Int       Date:  2013-06-30       Impact factor: 4.223

8.  Oral Soft Tissue Regeneration Using Nano Controlled System Inducing Sequential Release of Trichloroacetic Acid and Epidermal Growth Factor.

Authors:  Kwang Man Park; Hong Jae Lee; Ki-Tae Koo; Heithem Ben Amara; Richard Leesungbok; Kwantae Noh; Sang Cheon Lee; Suk Won Lee
Journal:  Tissue Eng Regen Med       Date:  2020-01-22       Impact factor: 4.169

9.  Chemical Regeneration of Wound Defects: Relevance to the Canine Palatal Mucosa and Cell Cycle Up-Regulation in Human Gingival Fibroblasts.

Authors:  Kyungho Lee; Heithem Ben Amara; Sang Cheon Lee; Richard Leesungbok; Min Ah Chung; Ki-Tae Koo; Suk Won Lee
Journal:  Tissue Eng Regen Med       Date:  2019-11-21       Impact factor: 4.169

Review 10.  Acne Scarring-Pathogenesis, Evaluation, and Treatment Options.

Authors:  Deirdre Connolly; Ha Linh Vu; Kavita Mariwalla; Nazanin Saedi
Journal:  J Clin Aesthet Dermatol       Date:  2017-09-01
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