Literature DB >> 12459872

Ultrastructural criteria of malignancy of adrenal medullary tumor.

N T Raikhlin1, A A Baronin, E A Smirnova, N A Probatova, M I Bronshtein, O V Chistyakova, I A Bukaeva.   

Abstract

Histological analysis and electron microscopy of 12 benign pheochromocytomas and 9 malignant pheochromoblastomas showed that there are no reliable histological differences between cells of benign and malignant tumor of the adrenal medulla. The ratio of ultrastructurally differentiated and undifferentiated cells in the tumor can reflect their maturity; the more ultrastructurally undifferentiated and less differentiated cells in the tumor, the higher is the malignant potential of this tumor.

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Year:  2002        PMID: 12459872     DOI: 10.1023/a:1020616923868

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2).

Authors:  R Tofighi; B Joseph; S Xia; Z-Q D Xu; B Hamberger; T Hökfelt; S Ceccatelli
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-12       Impact factor: 11.205

  1 in total

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