Literature DB >> 12459732

Oncolytic viruses.

E Antonio Chiocca1.   

Abstract

Although the cytotoxic effects of viruses are usually viewed in terms of pathogenicity, it is possible to harness this activity for therapeutic purposes. Viral genomes are highly versatile, and can be modified to direct their cytotoxicity towards cancer cells. These viruses are known as oncolytic viruses. How are viruses engineered to become tumour specific, and can they be used to safely treat cancer in humans?

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Year:  2002        PMID： 12459732     DOI： 10.1038/nrc948

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  103 in total

1.  An intravenous stimulus package for oncolytic virotherapy.

Authors:  Richard Vile; Alan Melcher
Journal:  Mol Ther       Date:  2011-11       Impact factor: 11.454

2.  Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells.

Authors:  Marianela Candolfi; James F Curtin; Wei-Dong Xiong; Kurt M Kroeger; Chunyan Liu; Altan Rentsendorj; Hasmik Agadjanian; Lali Medina-Kauwe; Donna Palmer; Philip Ng; Pedro R Lowenstein; Maria G Castro
Journal:  Mol Ther       Date:  2006-06-23       Impact factor: 11.454

3.  In vitro detection of cholangiocarcinoma cells using a fluorescent protein-expressing oncolytic herpes virus.

Authors:  R J S Coelen; M J de Keijzer; R Weijer; V V Loukachov; J K Wiggers; F P J Mul; A C W A van Wijk; Y Fong; M Heger; T M van Gulik
Journal:  Cancer Gene Ther       Date:  2017-04-14       Impact factor: 5.987

4.  Adenoviral-mediated gene transfer into the canine brain in vivo.

Authors:  Marianela Candolfi; Kurt M Kroeger; G Elizabeth Pluhar; Josee Bergeron; Mariana Puntel; James F Curtin; Elizabeth A McNiel; Andrew B Freese; John R Ohlfest; Peter Moore; Pedro R Lowenstein; Maria G Castro
Journal:  Neurosurgery       Date:  2007-01       Impact factor: 4.654

5.  The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon.

Authors:  Christopher A Alvarez-Breckenridge; Jianhua Yu; Richard Price; Min Wei; Yan Wang; Michal O Nowicki; Yoonhee P Ha; Stephen Bergin; Christine Hwang; Soledad A Fernandez; Balveen Kaur; Michael A Caligiuri; E Antonio Chiocca
Journal:  J Virol       Date:  2012-02-08       Impact factor: 5.103

6.  Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses.

Authors:  Hong Jiang; Ramon Alemany; Candelaria Gomez-Manzano; Diana R Medrano; Michael G Lemoine; Melissa V Olson; Marta M Alonso; Ok-Hee Lee; Charles C Conrad; W K Alfred Yung; Juan Fueyo
Journal:  Neoplasia       Date:  2005-08       Impact factor: 5.715

Review 7.  Methods for gene transfer to the central nervous system.

Authors:  Boris Kantor; Rachel M Bailey; Keon Wimberly; Sahana N Kalburgi; Steven J Gray
Journal:  Adv Genet       Date:  2014       Impact factor: 1.944

8.  Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression.

Authors:  Marianela Candolfi; James F Curtin; W Stephen Nichols; Akm G Muhammad; Gwendalyn D King; G Elizabeth Pluhar; Elizabeth A McNiel; John R Ohlfest; Andrew B Freese; Peter F Moore; Jonathan Lerner; Pedro R Lowenstein; Maria G Castro
Journal:  J Neurooncol       Date:  2007-09-15       Impact factor: 4.130

9.  The targeted inhibitory effects of human amniotic fluid stem cells carrying CXCR4 promoter and DAL-1 on non-small cell lung carcinoma growth.

Authors:  L Li; S Li; T Cai; H Wang; X Xie; Z Liu; Y Zhang
Journal:  Gene Ther       Date:  2015-08-17       Impact factor: 5.250

10.  In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas.

Authors:  Mahmud Uzzaman; Gordon Keller; Isabelle M Germano
Journal:  Neuro Oncol       Date:  2008-08-01       Impact factor: 12.300
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