Literature DB >> 12459333

Advances in lentiviral vector design for gene-modification of hematopoietic stem cells.

Aaron C Logan1, Carolyn Lutzko, Donald B Kohn.   

Abstract

Lentiviral vectors are more efficient at transducing quiescent hematopoietic stem cells than murine retroviral vectors. This characteristic is due to multiple karyophilic components of the lentiviral vector pre-integration complex. Lentiviral vectors are also able to carry more complex payloads than murine retroviral vectors, making it possible to deliver expression cassettes that direct either constitutive or targeted expression in various hematopoietic stem cell progeny.

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Year:  2002        PMID： 12459333     DOI： 10.1016/s0958-1669(02)00346-4

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  23 in total

Review 1.  Therapy of erectile dysfunction: potential future treatments.

Authors:  Nestor F Gonzalez-Cadavid; Jacob Rajfer
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2.  Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies.

Authors:  W H Shuen; R Kan; Z Yu; H L Lung; M L Lung
Journal:  Cancer Gene Ther       Date:  2015-02-27       Impact factor: 5.987

3.  Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors.

Authors:  Hideki Hanawa; Derek A Persons; Arthur W Nienhuis
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

4.  HIV-1 Is Restricted prior to Integration of Viral DNA in Primary Cord-Derived Human CD34+ Cells.

Authors:  Daniel O Griffin; Stephen P Goff
Journal:  J Virol       Date:  2015-08       Impact factor: 5.103

5.  Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes.

Authors:  M Lee Lucas; Nancy E Seidel; Christopher D Porada; John G Quigley; Stacie M Anderson; Harry L Malech; Janis L Abkowitz; Esmail D Zanjani; David M Bodine
Journal:  Blood       Date:  2005-03-17       Impact factor: 22.113

6.  Design and in vivo characterization of self-inactivating human and non-human lentiviral expression vectors engineered for streptogramin-adjustable transgene expression.

Authors:  Barbara Mitta; Cornelia C Weber; Markus Rimann; Martin Fussenegger
Journal:  Nucleic Acids Res       Date:  2004-07-16       Impact factor: 16.971

Review 7.  Lentiviral vectors for immune cells targeting.

Authors:  Steven Froelich; April Tai; Pin Wang
Journal:  Immunopharmacol Immunotoxicol       Date:  2010-06       Impact factor: 2.730

8.  CTD small phosphatase like 2 (CTDSPL2) can increase ε- and γ-globin gene expression in K562 cells and CD34+ cells derived from umbilical cord blood.

Authors:  Yan-Ni Ma; Xin Zhang; Hai-Chuan Yu; Jun-Wu Zhang
Journal:  BMC Cell Biol       Date:  2010-10-09       Impact factor: 4.241

Review 9.  Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells.

Authors:  Axel Schambach; Christopher Baum
Journal:  DNA Repair (Amst)       Date:  2007-05-07

10.  Targeted gene delivery to CD117-expressing cells in vivo with lentiviral vectors co-displaying stem cell factor and a fusogenic molecule.

Authors:  Steven Froelich; Leslie Ziegler; Katie Stroup; Pin Wang
Journal:  Biotechnol Bioeng       Date:  2009-09-01       Impact factor: 4.530
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