Literature DB >> 12458949

Analysis of anthraquinones in Rubia tinctorum L. by liquid chromatography coupled with diode-array UV and mass spectrometric detection.

Goverdina C H Derksen1, Harm A G Niederländer, Teris A van Beek.   

Abstract

A liquid chromatographic (LC) method for the separation of both anthraquinone glycosides and aglycones in extracts of Rubia tinctorum was improved. For on-line MS detection atmospheric pressure chemical ionisation as well as electrospray ionisation (ESI) were used. The glycosides were ionised in both positive and negative ionisation (NI) mode, the aglycones only in the NI mode. With ESI ammonia was added to the eluent post-column to deprotonate the compounds. The efficiency of mass detection of the hydroxyanthraquinone aglycones was found to depend on the pKa value of the component. LC-diode-array detection and LC-MS provide useful complementary information for the identification of anthraquinones in plant extracts, which was proven with the identification of munjistin and pseudopurpurin.

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Year:  2002        PMID: 12458949     DOI: 10.1016/s0021-9673(02)01412-7

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  9 in total

1.  Optimization of ultrasound and microwave assisted extractions of polyphenols from black rice (Oryza sativa cv. Poireton) husk.

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2.  Determination of pharmacologically active compounds in root extracts of Cassia alata L. by use of high performance liquid chromatography.

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Journal:  Int J Mol Sci       Date:  2012-03-13       Impact factor: 6.208

4.  Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1).

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Review 5.  Naturally occurring anthraquinones: chemistry and therapeutic potential in autoimmune diabetes.

Authors:  Shih-Chang Chien; Yueh-Chen Wu; Zeng-Weng Chen; Wen-Chin Yang
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6.  Early evidence (late 2nd millennium BCE) of plant-based dyeing of textiles from Timna, Israel.

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7.  In vitro Antiviral Activity of Rubia cordifolia Aerial Part Extract against Rotavirus.

Authors:  Yuanyuan Sun; Xuepeng Gong; Jia Y Tan; Lifeng Kang; Dongyan Li; Jihong Yang; Guang Du
Journal:  Front Pharmacol       Date:  2016-09-13       Impact factor: 5.810

8.  Towards hydrophobic carminic acid derivatives and their incorporation in polyacrylates.

Authors:  Luca Gabrielli; Davide Origgi; Giuseppe Zampella; Luca Bertini; Simone Bonetti; Gianfranco Vaccaro; Francesco Meinardi; Roberto Simonutti; Laura Cipolla
Journal:  R Soc Open Sci       Date:  2018-07-04       Impact factor: 2.963

9.  HPTLC-DESI-HRMS-Based Profiling of Anthraquinones in Complex Mixtures-A Proof-of-Concept Study Using Crude Extracts of Chilean Mushrooms.

Authors:  Annegret Laub; Ann-Katrin Sendatzki; Götz Palfner; Ludger A Wessjohann; Jürgen Schmidt; Norbert Arnold
Journal:  Foods       Date:  2020-02-06
  9 in total

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