Post-radiation angiosarcoma and bilateral mastectomy.

We report the occurrence of bilateral angiosarcoma after radiation therapy for breast carcinoma in a 64 yr-old woman. The first angiosarcoma developed 17 yr after radiation therapy to the right breast; the second angiosarcoma developed 1.5 yr after radiation therapy to the left breast. Recognizing angiosarcoma in radiated breast tissue is essential to appropriate therapy. The role of irradiation after surgery as adjuvant therapy is to be reviewed.