| Literature DB >> 12457704 |
Abstract
Analysis of senescent Escherichia coli cells reveals a link between protein oxidation and the fidelity of the translational apparatus. This model system has also provided a mechanistic molecular explanation for a trade-off between reproduction and survival activities, which may inspire proponents of the disposable soma theory and antagonistic pleiotropy hypothesis of aging.Entities:
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Year: 2002 PMID: 12457704 DOI: 10.1016/s1369-5274(02)00367-3
Source DB: PubMed Journal: Curr Opin Microbiol ISSN: 1369-5274 Impact factor: 7.934