S J Bowman1. 1. Rheumatology Department, Division of Immunity and Infection, The Medical School, University of Birmingham, UK. s.j.bowman@bham.ac.uk
Abstract
OBJECTIVE: To inform clinical rheumatologists about the common and rarer hematological manifestations of rheumatoid arthritis with an emphasis on diagnosis and therapy and a particular reference to Felty's syndrome. METHODS: Literature review. RESULTS: The hematological manifestations can be conveniently categorized into the broad areas of; anemia, particularly NSAID induced iron deficiency anemia and the anemia of chronic disease, neutropenia, particularly Felty's syndrome and the large granular lymphocyte syndrome and drug induced neutropenia; thrombocytopenia, particularly autoimmune and drug induced thrombocytopenia; and hematological malignancy. Rarer conditions, their diagnosis and therapy are also described in this review. CONCLUSION: Hematological manifestations of rheumatoid arthritis are very common. A logical approach using easily available tests should allow straightforward decisions about diagnosis and therapy to be made, even in patients with some of the rarer manifestations.
OBJECTIVE: To inform clinical rheumatologists about the common and rarer hematological manifestations of rheumatoid arthritis with an emphasis on diagnosis and therapy and a particular reference to Felty's syndrome. METHODS: Literature review. RESULTS: The hematological manifestations can be conveniently categorized into the broad areas of; anemia, particularly NSAID induced iron deficiency anemia and the anemia of chronic disease, neutropenia, particularly Felty's syndrome and the large granular lymphocyte syndrome and drug induced neutropenia; thrombocytopenia, particularly autoimmune and drug induced thrombocytopenia; and hematological malignancy. Rarer conditions, their diagnosis and therapy are also described in this review. CONCLUSION: Hematological manifestations of rheumatoid arthritis are very common. A logical approach using easily available tests should allow straightforward decisions about diagnosis and therapy to be made, even in patients with some of the rarer manifestations.
Authors: Magen L Shaughnessy; Susannah J Sample; Carter Abicht; Caitlin Heaton; Peter Muir Journal: J Am Vet Med Assoc Date: 2016-11-15 Impact factor: 1.936
Authors: Aymun Madni Zubair; Muhammad Nasir Hayat Malik; Waqas Younis; Muhammad Atif Hayat Malik; Shah Jahan; Ishtiaq Ahmed; Alamgeer Yuchi; Muhammad Naveed Mushtaq; Romeeza Tahir; Muhammad Bilal Sarwar; Muhammad Roman; Ayaz Ali Khan; Muhammad Nouman Tahir; Muhammad Tariq Khan; Hafiz Amir Ali Kharl; Gagun Kamran; Abdullah Abdo Albegali; Ali Imran Journal: Inflammopharmacology Date: 2022-04-16 Impact factor: 4.473