Literature DB >> 1245552

Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography.

D L Price, A Stocks, J W Griffin, A Young, K Peck.   

Abstract

Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that [3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons.

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Year:  1976        PMID： 1245552      PMCID： PMC2109627          DOI： 10.1083/jcb.68.2.389

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  18 in total

1.  The time courses of excitatory and inhibitory synaptic actions.

Authors:  D R CURTIS; J C ECCLES
Journal:  J Physiol       Date:  1959-03-12       Impact factor: 5.182

2.  Association of glycine with spinal interneurones.

Authors:  R A Davidoff; R P Shank; L T Graham; M H Aprison; R Werman
Journal:  Nature       Date:  1967-05-13       Impact factor: 49.962

3.  Autoradiographic uptake patterns of (3H)GABA and (3H)glycine in central nervous tissues with special reference to the cat spinal cord.

Authors:  A Ljungdahl; T Hökfelt
Journal:  Brain Res       Date:  1973-11-23       Impact factor: 3.252

4.  Uptake of 14C glycine by spinal cord.

Authors:  M J Neal; H G Pickles
Journal:  Nature       Date:  1969-05-17       Impact factor: 49.962

5.  The hyperpolarization of spinal motoneurones by glycine and related amino acids.

Authors:  D R Curtis; L Hösli; G A Johnston; I H Johnston
Journal:  Exp Brain Res       Date:  1968       Impact factor: 1.972

6.  Spatial synaptic distribution of recurrent and group Ia inhibitory systems in cat spinal motoneurones.

Authors:  R E Burke; L Fedina; A Lundberg
Journal:  J Physiol       Date:  1971-04       Impact factor: 5.182

7.  The uptake of [14C]glycine by slices of mammalian spinal cord.

Authors:  M J Neal
Journal:  J Physiol       Date:  1971-05       Impact factor: 5.182

8.  Studies of the uptake of 3 H-gaba and ( 3 H)glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography.

Authors:  L L Iversen; F E Bloom
Journal:  Brain Res       Date:  1972-06-08       Impact factor: 3.252

9.  An artefact in radioautography due to binding of free amino acids to tissues by fixatives.

Authors:  T Peters; C A Ashley
Journal:  J Cell Biol       Date:  1967-04       Impact factor: 10.539

10.  Glutamate uptake by a stimulated insect nerve muscle preparation.

Authors:  I R Faeder; M M Salpeter
Journal:  J Cell Biol       Date:  1970-08       Impact factor: 10.539
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  4 in total

Review 1.  Quantitative electron microscopic immunocytochemistry of neuroactive amino acids.

Authors:  O P Ottersen
Journal:  Anat Embryol (Berl)       Date:  1989

2.  Early history of glycine receptor biology in Mammalian spinal cord circuits.

Authors:  Robert John Callister; Brett Anthony Graham
Journal:  Front Mol Neurosci       Date:  2010-05-21       Impact factor: 5.639

3.  Glycine-like immunoreactivity in the cerebellum of rat and Senegalese baboon, Papio papio: a comparison with the distribution of GABA-like immunoreactivity and with [3H]glycine and [3H]GABA uptake.

Authors:  O P Ottersen; S Davanger; J Storm-Mathisen
Journal:  Exp Brain Res       Date:  1987       Impact factor: 1.972

4.  The uptake and release of [3H]glycine in the goldfish retina.

Authors:  C A Chin; D M Lam
Journal:  J Physiol       Date:  1980-11       Impact factor: 5.182
  4 in total

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