| Literature DB >> 12454646 |
Rodrigo F Chuaqui1, Robert F Bonner, Carolyn J M Best, John W Gillespie, Michael J Flaig, Stephen M Hewitt, John L Phillips, David B Krizman, Michael A Tangrea, Mamoun Ahram, W Marston Linehan, Vladimir Knezevic, Michael R Emmert-Buck.
Abstract
Measurement of gene-expression profiles using microarray technology is becoming increasingly popular among the biomedical research community. Although there has been great progress in this field, investigators are still confronted with a difficult question after completing their experiments: how to validate the large data sets that are generated? This review summarizes current approaches to verifying global expression results, discusses the caveats that must be considered, and describes some methods that are being developed to address outstanding problems.Mesh：
Substances：
Year: 2002 PMID： 12454646 DOI： 10.1038/ng1034
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330