Literature DB >> 1245440

Immunological decay in thymectomized infants.

A Rubinstein, B Pelet, V Schweizer.   

Abstract

Four infants underwent radical thymectomy for a suspected malignancy of the thymus. Histology revealed no malignant cells. The patients did clinically well as long as 14 years after the operation. There was laboratory evidence for a cellular and humoral immunodeficiency. Affected were mainly the response to oral poliomyelitis vaccinations and the skin tests of delayed type hypersensitivity.

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Year:  1976        PMID: 1245440

Source DB:  PubMed          Journal:  Helv Paediatr Acta        ISSN: 0018-022X


  5 in total

Review 1.  The role of the thymus in immunosenescence: lessons from the study of thymectomized individuals.

Authors:  Victor Appay; Delphine Sauce; Martina Prelog
Journal:  Aging (Albany NY)       Date:  2010-03-20       Impact factor: 5.682

2.  Evidence of premature immune aging in patients thymectomized during early childhood.

Authors:  Delphine Sauce; Martin Larsen; Solène Fastenackels; Anne Duperrier; Michael Keller; Beatrix Grubeck-Loebenstein; Christophe Ferrand; Patrice Debré; Daniel Sidi; Victor Appay
Journal:  J Clin Invest       Date:  2009-09-21       Impact factor: 14.808

3.  Antihelper T cell autoantibody in acquired agammaglobulinemia.

Authors:  A Rubinstein; M Sicklick; V Mehra; F S Rosen; R H Levey
Journal:  J Clin Invest       Date:  1981-01       Impact factor: 14.808

4.  The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in life.

Authors:  J H Eysteinsdottir; J Freysdottir; A Haraldsson; J Stefansdottir; I Skaftadottir; H Helgason; H M Ogmundsdottir
Journal:  Clin Exp Immunol       Date:  2004-05       Impact factor: 4.330

5.  Immunodeficiency following neonatal thymectomy in man.

Authors:  S Brearley; T A Gentle; M I Baynham; K D Roberts; L D Abrams; R A Thompson
Journal:  Clin Exp Immunol       Date:  1987-11       Impact factor: 4.330

  5 in total

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