Literature DB >> 12454259

Lipoprotein lipase: genetics, lipid uptake, and regulation.

Martin Merkel1, Robert H Eckel, Ira J Goldberg.   

Abstract

Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed. 2) LPL actions in the nervous system, liver, and heart: the discussion focuses on LPL and tissue lipid uptake. 3) LPL gene regulation: the LPL promoter and its regulatory elements are described.

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Year:  2002        PMID： 12454259     DOI： 10.1194/jlr.r200015-jlr200

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


  160 in total

1.  GPR103b functions in the peripheral regulation of adipogenesis.

Authors:  Mukandila Mulumba; Christian Jossart; Riccarda Granata; Davide Gallo; Emanuel Escher; Ezio Ghigo; Marc J Servant; Sylvie Marleau; Huy Ong
Journal:  Mol Endocrinol       Date:  2010-06-09

2.  Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1.

Authors:  Constance V Voss; Brandon S J Davies; Shelly Tat; Peter Gin; Loren G Fong; Christopher Pelletier; Charlene D Mottler; André Bensadoun; Anne P Beigneux; Stephen G Young
Journal:  Proc Natl Acad Sci U S A       Date:  2011-04-25       Impact factor: 11.205

Review 3.  The role of CREB-H transcription factor in triglyceride metabolism.

Authors:  Ann-Hwee Lee
Journal:  Curr Opin Lipidol       Date:  2012-04       Impact factor: 4.776

Review 4.  Give me A5 for lipoprotein hydrolysis!

Authors:  Martin Merkel; Joerg Heeren
Journal:  J Clin Invest       Date:  2005-10       Impact factor: 14.808

5.  Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids.

Authors:  Diego Scerbo; Ni-Huiping Son; Alaa Sirwi; Lixia Zeng; Kelli M Sas; Vincenza Cifarelli; Gabriele Schoiswohl; Lesley-Ann Huggins; Namrata Gumaste; Yunying Hu; Subramaniam Pennathur; Nada A Abumrad; Erin E Kershaw; M Mahmood Hussain; Katalin Susztak; Ira J Goldberg
Journal:  J Lipid Res       Date:  2017-04-12       Impact factor: 5.922

6.  Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.

Authors:  Stefano Romeo; Wu Yin; Julia Kozlitina; Len A Pennacchio; Eric Boerwinkle; Helen H Hobbs; Jonathan C Cohen
Journal:  J Clin Invest       Date:  2008-12-15       Impact factor: 14.808

7.  Impact of lipoprotein lipase gene polymorphisms on ulcerative colitis.

Authors:  Toshihito Kosaka; Junji Yoshino; Kazuo Inui; Takao Wakabayashi; Kazumu Okushima; Takashi Kobayashi; Hironao Miyoshi; Yuta Nakamura; Shigekazu Hayashi; Taizou Shiraishi; Masatoshi Watanabe; Takayuki Yamamoto; Ai Nakahara; Takahiko Katoh
Journal:  World J Gastroenterol       Date:  2006-10-21       Impact factor: 5.742

8.  Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Calpha activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA.

Authors:  Resat Unal; Irina Pokrovskaya; Preeti Tripathi; Brett P Monia; Philip A Kern; Gouri Ranganathan
Journal:  Biochem J       Date:  2008-07-15       Impact factor: 3.857

9.  Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site.

Authors:  Kris Richardson; Jennifer A Nettleton; Noemi Rotllan; Toshiko Tanaka; Caren E Smith; Chao-Qiang Lai; Laurence D Parnell; Yu-Chi Lee; Jari Lahti; Rozenn N Lemaitre; Ani Manichaikul; Margaux Keller; Vera Mikkilä; Julius Ngwa; Frank J A van Rooij; Christie M Ballentyne; Ingrid B Borecki; L Adrienne Cupples; Melissa Garcia; Albert Hofman; Luigi Ferrucci; Dariush Mozaffarian; Mia-Maria Perälä; Olli Raitakari; Russell P Tracy; Donna K Arnett; Stefania Bandinelli; Eric Boerwinkle; Johan G Eriksson; Oscar H Franco; Mika Kähönen; Michael Nalls; David S Siscovick; Denise K Houston; Bruce M Psaty; Jorma Viikari; Jacqueline C M Witteman; Mark O Goodarzi; Terho Lehtimäki; Yongmei Liu; M Carola Zillikens; Yii-Der I Chen; André G Uitterlinden; Jerome I Rotter; Carlos Fernandez-Hernando; Jose M Ordovas
Journal:  Am J Hum Genet       Date:  2012-12-13       Impact factor: 11.025

Review 10.  Lipoprotein lipase and its role in regulation of plasma lipoproteins and cardiac risk.

Authors:  Jila Kaberi Otarod; Ira J Goldberg
Journal:  Curr Atheroscler Rep       Date:  2004-09       Impact factor: 5.113
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