| Literature DB >> 1245386 |
S H Wray, T Kuwabara, P Sanderson.
Abstract
Light and electron microscopic studies of the ocular tissue of a case of Menkes' kinky hair disease are described. The copper deficiency responsible for this systemic and neurologic disease appears to cause a progressive degeneration of retinal ganglion cells, loss of nerve fibers, and optic atrophy. The pigment epithelium is also abnormal with only small and irregular melanin granules present among electron-dense inclusion bodies. Abnormal elastica is present in Bruch's membrane.Entities:
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Year: 1976 PMID： 1245386
Source DB: PubMed Journal: Invest Ophthalmol ISSN： 0020-9988