| Literature DB >> 12452881 |
M M U Chowdhury1, E J Williams, J S Morris, B J M Ferguson, A D McGregor, A R Hedges, J D Stamatakis, F M Pope.
Abstract
Severe panniculitis caused by alpha1-antitrypsin deficiency is very rare even though the ZZ phenotype occurs in 1 : 3500 of the population of northern Europe. We describe a 33-year-old woman with rapidly progressing panniculitis and extensive skin necrosis with multiple life-threatening complications. Initial treatment followed by maintenance therapy with human purified enzyme (Prolastin, Bayer, Bridgend, U.K.) has been life-saving.Entities:
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Year: 2002 PMID： 12452881 DOI： 10.1046/j.1365-2133.2002.05095.x
Source DB: PubMed Journal: Br J Dermatol ISSN： 0007-0963 Impact factor: 9.302