Literature DB >> 12452683

A short, highly efficient synthesis of coenzyme Q(10).

Bruce H Lipshutz1, Paul Mollard, Steven S Pfeiffer, Will Chrisman.   

Abstract

The most efficient synthesis reported to date of ubiquinone (CoQ10) is described. A sequence consisting of six operations is involved which leads to crystalline material in an overall yield of >64%.

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Year:  2002        PMID: 12452683     DOI: 10.1021/ja021015v

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  7 in total

1.  Coenzyme Q10 production in a 150-l reactor by a mutant strain of Rhodobacter sphaeroides.

Authors:  Nguyen Ba Kien; In-Soo Kong; Min-Gyu Lee; Joong Kyun Kim
Journal:  J Ind Microbiol Biotechnol       Date:  2010-02-27       Impact factor: 3.346

2.  Coenzyme Q10 in the eye isomerizes by sunlight irradiation.

Authors:  Md Al Mamun; Md Mahamodun Nabi; Tomohito Sato; Shuhei Aramaki; Yusuke Takanashi; Takumi Sakamoto; Kaito Hizume; Chikako Mori; Maiha Yasue; Masataka Ozaki; Ariful Islam; Tomoaki Kahyo; Makoto Horikawa; Yutaka Takahashi; Shigetoshi Okazaki; Kentaro Ohishi; Yu Nagashima; Keiji Seno; Yoshihiro Hotta; Mitsutoshi Setou
Journal:  Sci Rep       Date:  2022-07-15       Impact factor: 4.996

Review 3.  CoQ10 a super-vitamin: review on application and biosynthesis.

Authors:  Shraddha Shukla; Kashyap Kumar Dubey
Journal:  3 Biotech       Date:  2018-05-09       Impact factor: 2.406

4.  Enhanced production of CoQ10 by newly isolated Sphingomonas sp. ZUTEO3 with a coupled fermentation-extraction process.

Authors:  Weihong Zhong; Jianjun Fang; Huagui Liu; Xin Wang
Journal:  J Ind Microbiol Biotechnol       Date:  2009-02-17       Impact factor: 3.346

5.  Efficient Lewis acid ionic liquid-catalyzed synthesis of the key intermediate of coenzyme Q10 under microwave irradiation.

Authors:  Yue Chen; Yuangang Zu; Yujie Fu; Xuan Zhang; Ping Yu; Guoyong Sun; Thomas Efferth
Journal:  Molecules       Date:  2010-12-22       Impact factor: 4.411

6.  Propargylation of CoQ0 through the Redox Chain Reaction.

Authors:  Robert Pawlowski; Maciej Stodulski; Jacek Mlynarski
Journal:  J Org Chem       Date:  2021-12-21       Impact factor: 4.354

7.  Preparation of Key Intermediates for the Syntheses of Coenzyme Q10 and Derivatives by Cross-Metathesis Reactions.

Authors:  Trang Nguyen; Hung Mac; Phong Pham
Journal:  Molecules       Date:  2020-01-21       Impact factor: 4.411

  7 in total

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