Literature DB >> 12452569

Label-free bioaffinity detection using terahertz technology.

Samuel P Mickan1, Abdellah Menikh, Haibo Liu, Carmen A Mannella, Robert MacColl, Derek Abbott, Jesper Munch, X C Zhang.   

Abstract

We report the first use of differential terahertz time-domain spectroscopy for bioaffinity sensing. Binding is observed by measuring the transmission of a thin layer of biotin bound to the sensor protein avidin. We demonstrate the THz wave transmission of a sub-micron-thick film and sensitivity to 0.1 microg cm(-2) of biotin. These results point the way for a host of biosensor applications using T-rays, or pulsed far-infrared (FIR) radiation.

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Year:  2002        PMID： 12452569     DOI： 10.1088/0031-9155/47/21/317

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN： 0031-9155            Impact factor:   3.609


  13 in total

1.  Sensing viruses using terahertz nano-gap metamaterials.

Authors:  S J Park; S H Cha; G A Shin; Y H Ahn
Journal:  Biomed Opt Express       Date:  2017-07-07       Impact factor: 3.732

2.  Ultrasensitive THz biosensor for PCR-free cDNA detection based on frequency selective surfaces.

Authors:  Christian Weisenstein; Dominik Schaar; Anna Katharina Wigger; Heiko Schäfer-Eberwein; Anja K Bosserhoff; Peter Haring Bolívar
Journal:  Biomed Opt Express       Date:  2019-12-23       Impact factor: 3.732

3.  Non-thermal effects of terahertz radiation on gene expression in mouse stem cells.

Authors:  Boian S Alexandrov; Kim Ø Rasmussen; Alan R Bishop; Anny Usheva; Ludmil B Alexandrov; Shou Chong; Yossi Dagon; Layla G Booshehri; Charles H Mielke; M Lisa Phipps; Jennifer S Martinez; Hou-Tong Chen; George Rodriguez
Journal:  Biomed Opt Express       Date:  2011-08-23       Impact factor: 3.732

4.  Metamaterials application in sensing.

Authors:  Tao Chen; Suyan Li; Hui Sun
Journal:  Sensors (Basel)       Date:  2012-02-29       Impact factor: 3.576

5.  Extraordinary sensitivity enhancement by metasurfaces in terahertz detection of antibiotics.

Authors:  Lijuan Xie; Weilu Gao; Jie Shu; Yibin Ying; Junichiro Kono
Journal:  Sci Rep       Date:  2015-03-02       Impact factor: 4.379

6.  A Route to Terahertz Metamaterial Biosensor Integrated with Microfluidics for Liver Cancer Biomarker Testing in Early Stage.

Authors:  Zhaoxin Geng; Xiong Zhang; Zhiyuan Fan; Xiaoqing Lv; Hongda Chen
Journal:  Sci Rep       Date:  2017-11-27       Impact factor: 4.379

7.  Terahertz Spectroscopic Diagnosis of Myelin Deficit Brain in Mice and Rhesus Monkey with Chemometric Techniques.

Authors:  Yi Zou; Jiang Li; Yiyuan Cui; Peiren Tang; Lianghui Du; Tunan Chen; Kun Meng; Qiao Liu; Hua Feng; Jianheng Zhao; Mina Chen; Li-Guo Zhu
Journal:  Sci Rep       Date:  2017-07-12       Impact factor: 4.379

8.  Detection of microorganisms using terahertz metamaterials.

Authors:  S J Park; J T Hong; S J Choi; H S Kim; W K Park; S T Han; J Y Park; S Lee; D S Kim; Y H Ahn
Journal:  Sci Rep       Date:  2014-05-16       Impact factor: 4.379

9.  Spectroscopic Terahertz Imaging at Room Temperature Employing Microbolometer Terahertz Sensors and Its Application to the Study of Carcinoma Tissues.

Authors:  Irmantas Kašalynas; Rimvydas Venckevičius; Linas Minkevičius; Aleksander Sešek; Faustino Wahaia; Vincas Tamošiūnas; Bogdan Voisiat; Dalius Seliuta; Gintaras Valušis; Andrej Švigelj; Janez Trontelj
Journal:  Sensors (Basel)       Date:  2016-03-25       Impact factor: 3.576

10.  Ultra-high dynamic range electro-optic sampling for detecting millimeter and sub-millimeter radiation.

Authors:  Akram Ibrahim; Denis Férachou; Gargi Sharma; Kanwarpal Singh; Marie Kirouac-Turmel; Tsuneyuki Ozaki
Journal:  Sci Rep       Date:  2016-03-15       Impact factor: 4.379
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