Literature DB >> 12452461

Multicentre study of fetal cardiac time intervals using magnetocardiography.

J Stinstra1, E Golbach, P van Leeuwen, S Lange, T Menendez, W Moshage, E Schleussner, C Kaehler, H Horigome, S Shigemitsu, M J Peters.   

Abstract

OBJECTIVE: A database with reference values of the durations of the various waveforms in a magnetocardiogram of fetuses in uncomplicated pregnancies is assessed. This database will be of help to discriminate between pathologic and healthy fetuses. A fetal magnetocardiogram is a recording of the magnetic field in a location near the maternal abdomen and reflects the electric activity within the fetal heart. It is a non-invasive method, which can be used with nearly 100% reliability from the 20th week of gestation onward.
DESIGN: Durations of the waveforms were assembled from averaged magnetocardiograms and statistically processed.
SETTING: Fetal magnetocardiograms were measured with different magnetocardiographs. All measurements were carried out in magnetically shielded rooms. SAMPLE: Fetal magnetocardiograms were obtained for 582 healthy patients.
METHOD: The durations of the waveforms were extracted from fetal magnetocardiograms measured at the cooperating centres. The variables collected included the duration of the P-wave, the PR interval, the PQ interval, the QRS complex, the QT interval and the T-wave and QTc value. The results were compared with values extracted from electrocardiograms of fetuses measured via electrodes attached to the maternal abdomen, from electrocardiograms measured during labour using a scalp electrode, and from electrocardiograms recorded in newborns, that were found in the literature. MAIN OUTCOME MEASURES: Values of the durations are given as a function of gestational age including the regression line as well as the bounds marking the 90%, 95% and 98% prediction interval.
RESULTS: The durations of the P-wave, the PR interval, the QRS complex, the QT interval and QTc value increase linearly with gestational age. The durations of the PQ interval and the T-wave are independent of fetal age.
CONCLUSION: The values found agree with those found in the literature. The scatter of the data is wide due to the variation in normal physiology, the measuring system and signal processing and the subjectivity of the researcher. However, the system can define normal ranges and may be used in diagnosis.

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Year:  2002        PMID: 12452461     DOI: 10.1046/j.1471-0528.2002.01057.x

Source DB:  PubMed          Journal:  BJOG        ISSN: 1470-0328            Impact factor:   6.531


  21 in total

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Authors:  Janette F Strasburger; Ronald T Wakai
Journal:  Nat Rev Cardiol       Date:  2010-05       Impact factor: 32.419

2.  Permutation entropy improves fetal behavioural state classification based on heart rate analysis from biomagnetic recordings in near term fetuses.

Authors:  B Frank; B Pompe; U Schneider; D Hoyer
Journal:  Med Biol Eng Comput       Date:  2006-03-17       Impact factor: 2.602

3.  Fetal magnetocardiogram waveform characteristics.

Authors:  Sarah A Strand; Janette F Strasburger; Ronald T Wakai
Journal:  Physiol Meas       Date:  2019-03-22       Impact factor: 2.833

Review 4.  Diagnosis and treatment of fetal arrhythmia.

Authors:  Annette Wacker-Gussmann; Janette F Strasburger; Bettina F Cuneo; Ronald T Wakai
Journal:  Am J Perinatol       Date:  2014-05-23       Impact factor: 1.862

5.  Feasibility of Non-invasive Fetal Electrocardiographic Interval Measurement in the Outpatient Clinical Setting.

Authors:  Ashish N Doshi; Paige Mass; Kevin R Cleary; Jeffrey P Moak; Kiyoe Funamoto; Yoshitaka Kimura; Ahsan H Khandoker; Anita Krishnan
Journal:  Pediatr Cardiol       Date:  2019-06-06       Impact factor: 1.655

6.  Feasibility of noninvasive fetal electrocardiographic monitoring in a clinical setting.

Authors:  Bhawna Arya; Rathinaswamy Govindan; Anita Krishnan; Adre Duplessis; Mary T Donofrio
Journal:  Pediatr Cardiol       Date:  2015-01-22       Impact factor: 1.655

7.  Assessment of fetal atrioventricular time intervals by tissue Doppler and pulse Doppler echocardiography: normal values and correlation with fetal electrocardiography.

Authors:  M Nii; R M Hamilton; L Fenwick; J C P Kingdom; K S Roman; E T Jaeggi
Journal:  Heart       Date:  2006-06-14       Impact factor: 5.994

8.  Correlation between fetal brain activity patterns and behavioral states: an exploratory fetal magnetoencephalography study.

Authors:  Naim Haddad; Rathinaswamy B Govindan; Srinivasan Vairavan; Eric Siegel; Jessica Temple; Hubert Preissl; Curtis L Lowery; Hari Eswaran
Journal:  Exp Neurol       Date:  2011-01-13       Impact factor: 5.330

9.  Maternal MCG interference cancellation using splined independent component subtraction.

Authors:  Suhong Yu; Ronald T Wakai
Journal:  IEEE Trans Biomed Eng       Date:  2011-06-27       Impact factor: 4.538

10.  Cardiac vectors in the healthy human fetus: developmental changes assessed by magnetocardiography and realistic approximations of the volume conductor.

Authors:  R Tao; E A Popescu; W B Drake; M Popescu
Journal:  Physiol Meas       Date:  2013-04-22       Impact factor: 2.833

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