OBJECTIVE: To study the effects of Lycium barbarum polysaccharide (LBP) on alloxan-induced isolated islet cells damage in rats. METHODS: Isolated islet cells from SD rat were cultured in vitro. SOD activity and MDA content in rat islet cells incubated with alloxan or alloxan combined LBP were measured. RESULTS: Alloxan induced a significant decrease in SOD activity and a increase in MDA production, which were inhibited by LBP. CONCLUSION: LBP had protective effects on alloxan-induced isolated rat islet ceus damage.
OBJECTIVE: To study the effects of Lycium barbarum polysaccharide (LBP) on alloxan-induced isolated islet cells damage in rats. METHODS: Isolated islet cells from SD rat were cultured in vitro. SOD activity and MDA content in rat islet cells incubated with alloxan or alloxan combined LBP were measured. RESULTS:Alloxan induced a significant decrease in SOD activity and a increase in MDA production, which were inhibited by LBP. CONCLUSION: LBP had protective effects on alloxan-induced isolated rat islet ceus damage.