Literature DB >> 12451487

Cytotoxic amides from Piper sintenense.

Jih-Jung Chen1, Yu-Chun Huang, Yu-Chang Chen, Yao-Ting Huang, Shih-Wei Wang, Chieh-Yu Peng, Che-Ming Teng, Ih-Sheng Chen.   

Abstract

A new alkaloid, pipersintenamide ( 1), together with fourteen known compounds, have been isolated from the whole plant of Piper sintenense. The structures of these compounds were elucidated by spectroscopic analysis. Pipersintenamide, sintenpyridone, sarmentine, and 1-(3,4-methylenedioxyphenyl)-1 E-dodecene at 20 microg/ml exhibited effective cytotoxicities (cell survival < 15 %) against CCRF-CEM, HL-60, PC-3, and HA22T cell lines.

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Year:  2002        PMID: 12451487     DOI: 10.1055/s-2002-35660

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  2 in total

1.  HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site.

Authors:  Janine Zaugg; Igor Baburin; Barbara Strommer; Hyun-Jung Kim; Steffen Hering; Matthias Hamburger
Journal:  J Nat Prod       Date:  2010-02-26       Impact factor: 4.050

Review 2.  Anticancer principles from medicinal piper ( hú jiāo) plants.

Authors:  Yue-Hu Wang; Susan L Morris-Natschke; Jun Yang; Hong-Mei Niu; Chun-Lin Long; Kuo-Hsiung Lee
Journal:  J Tradit Complement Med       Date:  2014-01
  2 in total

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