Literature DB >> 12450789

Switching from life to death: the Miz-ing link between Myc and p53.

Karen H Vousden1.   

Abstract

Cells can respond to the activation of the tumor suppressor protein p53 by undergoing cell cycle arrest or apoptosis, and Myc has now been shown to help switch the response to apoptosis by repressing the expression of p21(CIP1), a cyclin-dependent kinase inhibitor with antiapoptotic activity.

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Year:  2002        PMID： 12450789     DOI： 10.1016/s1535-6108(02)00186-1

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  18 in total

1.  c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.

Authors:  Yinshi Guo; Chao Niu; Peter Breslin; Minghui Tang; Shubin Zhang; Wei Wei; Ameet R Kini; Gladell P Paner; Serhan Alkan; Stephan W Morris; Manuel Diaz; Patrick J Stiff; Jiwang Zhang
Journal:  Blood       Date:  2009-04-16       Impact factor: 22.113

2.  Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspases.

Authors:  Edward A Acheampong; Zahida Parveen; Lois W Muthoga; Mehrnush Kalayeh; Muhammad Mukhtar; Roger J Pomerantz
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

3.  Polyacetylenes function as anti-angiogenic agents.

Authors:  Li-Wha Wu; Yi-Ming Chiang; Hsiao-Ching Chuang; Sheng-Yang Wang; Ga-Wen Yang; Ya-huey Chen; Ling-Ya Lai; Lie-Fen Shyur
Journal:  Pharm Res       Date:  2004-11       Impact factor: 4.200

4.  Polyamine-modulated c-Myc expression in normal intestinal epithelial cells regulates p21Cip1 transcription through a proximal promoter region.

Authors:  Lan Liu; Xin Guo; Jaladanki N Rao; Tongtong Zou; Bernard S Marasa; Jie Chen; Jose Greenspon; Robert A Casero; Jian-Ying Wang
Journal:  Biochem J       Date:  2006-09-01       Impact factor: 3.857

5.  T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.

Authors:  Hui Feng; David L Stachura; Richard M White; Alejandro Gutierrez; Lu Zhang; Takaomi Sanda; Cicely A Jette; Joseph R Testa; Donna S Neuberg; David M Langenau; Jeffery L Kutok; Leonard I Zon; David Traver; Mark D Fleming; John P Kanki; A Thomas Look
Journal:  Cancer Cell       Date:  2010-10-19       Impact factor: 31.743

6.  p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels.

Authors:  N Gopalakrishna Iyer; Suet-Feung Chin; Hilal Ozdag; Yataro Daigo; De-En Hu; Massimiliano Cariati; Kevin Brindle; Samuel Aparicio; Carlos Caldas
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-27       Impact factor: 11.205

Review 7.  Regulation of apoptosis-related genes by nitric oxide in cancer.

Authors:  Samuel Y Olson; Hermes J Garbán
Journal:  Nitric Oxide       Date:  2008-06-02       Impact factor: 4.427

8.  Potential role of p53 mutation in chemical hepatocarcinogenesis of rats.

Authors:  Wei-Guo Deng; Yan Fu; Yu-Lin Li; Toshihiro Sugiyama
Journal:  World J Gastroenterol       Date:  2004-01       Impact factor: 5.742

9.  p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1.

Authors:  Sonia Rocha; Anthea M Martin; David W Meek; Neil D Perkins
Journal:  Mol Cell Biol       Date:  2003-07       Impact factor: 4.272

Review 10.  Cancer-Targeting Nanoparticles for Combinatorial Nucleic Acid Delivery.

Authors:  Hannah J Vaughan; Jordan J Green; Stephany Y Tzeng
Journal:  Adv Mater       Date:  2019-06-20       Impact factor: 30.849
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