Literature DB >> 12449733

Intracaval and intracardiac metastatic nonseminomatous germ cell tumor: a rare cause of hemolytic anemia and thrombocytopenia.

Ari D Fishman1, Anthony Hoffman, Fabio Volterra, Michael Frymus, Marco Gentilluci.   

Abstract

Intracaval and intracardiac nonseminomatous germ cell tumor metastases although rare have been previously reported in the literature. Most cases arise as a result of direct hematogenous spread via invasion of the internal spermatic vein, or from lymphatic venous shunting. We report a unique case of disseminated testicular germ cell tumor that presented with extensive intracaval and intracardiac metastatic teratoma and with valvular involvement. These findings were heralded by the presence of a new cardiac murmur, anemia, and severe thrombocytopenia. Resection of the intracardiac mass, prompted by rapid tumor progression despite treatment with systemic chemotherapy, demonstrated mature teratoma and resulted in prompt normalization of the patients hematologic profile.

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Year:  2002        PMID: 12449733     DOI: 10.1081/cnv-120005916

Source DB:  PubMed          Journal:  Cancer Invest        ISSN: 0735-7907            Impact factor:   2.176


  7 in total

1.  Intracardiac metastasis from germ cell testicular tumor.

Authors:  Z S Jonjev; J Rajić; M Majin; D Donat
Journal:  Herz       Date:  2012-02-25       Impact factor: 1.443

2.  Intracardiac Metastatic Sarcoma.

Authors:  J Louro; T Villanueva; J Freire; M J Passos
Journal:  Case Rep Oncol       Date:  2010-11-29

3.  Fatal thrombocytopenia: A rare case with possible explanation.

Authors:  Ramachandra Barik; A N Patnaik; A S Gulati
Journal:  J Cardiovasc Dis Res       Date:  2012-04

4.  Fatal thrombocytopenia associated with intracardiac mass.

Authors:  Kan Chen
Journal:  J Cardiovasc Dis Res       Date:  2012-04

5.  Mixed germ cell testicular cancer with left ventricular metastasis presenting with embolic stroke and small bowel tumor seeding.

Authors:  Srinath Sundararajan; Beth Braunhut; Frederick Ahmann; Amit Agarwal
Journal:  Case Rep Oncol Med       Date:  2014-06-18

6.  Huge right ventricular mass revealing a testicular nonseminomatous germ cell tumor.

Authors:  Jamal El Ouazzani; Mustapha Beghi; Amine Kossir; Nabila Ismaili; Noha El Ouafi
Journal:  J Saudi Heart Assoc       Date:  2018-02-24

7.  A rare cause in etiology of left atrial mass: metastatic testicular germ cell tumor.

Authors:  Serhat Huseyin; Volkan Yüksel; Ahmet Okyay; İlhan Hacıbekiroğlu; Ebru Tastekin; Mustafa Yılmaztepe; Gökay Taylan; Suat Canbaz; İrfan Çiçin
Journal:  Kardiochir Torakochirurgia Pol       Date:  2016-03-30
  7 in total

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