Literature DB >> 12448776

Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean.

Manuela Malatesta1, Chiara Caporaloni, Luigia Rossi, Serafina Battistelli, Marco B L Rocchi, Francesco Tonucci, Giancarlo Gazzanelli.   

Abstract

No direct evidence that genetically modified (GM) food may represent a possible danger for health has been reported so far; however, the scientific literature in this field is quite poor. Therefore, we investigated the possible effects of a diet containing GM soybean on mouse exocrine pancreas by means of ultrastructural, morphometrical and immunocytochemical analyses. Our observations demonstrate that, although no structural modification occurs in pancreatic acinar cells of mice fed on GM soybean, quantitative changes of some cellular constituents take place in comparison to control animals. In particular, a diet containing significant amount of GM food seems to influence the zymogen synthesis and processing.

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Year:  2002        PMID: 12448776      PMCID: PMC1570979          DOI: 10.1046/j.0021-8782.2002.00103.x

Source DB:  PubMed          Journal:  J Anat        ISSN: 0021-8782            Impact factor:   2.610


  23 in total

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Journal:  Science       Date:  1981-07-17       Impact factor: 47.728

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Journal:  Adv Exp Med Biol       Date:  1984       Impact factor: 2.622

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Journal:  Poult Sci       Date:  2000-04       Impact factor: 3.352

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Journal:  Br Med Bull       Date:  2000       Impact factor: 4.291

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  8 in total

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6.  Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize.

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Journal:  Environ Sci Eur       Date:  2014-06-24       Impact factor: 5.893

7.  Assessment of the impact of genetically modified LibertyLink® maize on reproductive function and progeny development of Wistar rats in three generations.

Authors:  N V Tyshko; V M Zhminchenko; K E Selyaskin; V A Pashorina; N T Utembaeva; V A Tutelyan
Journal:  Toxicol Rep       Date:  2014-06-11

8.  Roundup®, but Not Roundup-Ready® Corn, Increases Mortality of Drosophila melanogaster.

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  8 in total

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