Literature DB >> 1244859

Alpha-Glutamyl-beta-naphthylamide hydrolase of rabbit small intestine. Localization in the brush border and separation from other brush border peptidases.

G Andria, A Marzi, S Auricchio.   

Abstract

About 70% of the total mucosal enzymatic activity hydrolyzing beta-L-glutamyl-beta-naphthylamide in the rabbit small intestine is present in the brush border; the specific activity in this subcellular fraction is 7 times higher than that of the homogenate. Similar results are obtained for L-leucyl beta-naphthylamide hydrolase. The enzyme activity is efficiently solubilized by papain digestion and is clearly separated from L-leucyl-beta-naphthylamide hydrolase by chromatography on concanavalin A-Sepharose. It probably represents a digestive peptidase, different from the other known peptide hydrolases of the digestive surface of the small intestine.

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Year:  1976        PMID: 1244859     DOI: 10.1016/0005-2736(76)90370-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  4 in total

1.  Sourdough bread made from wheat and nontoxic flours and started with selected lactobacilli is tolerated in celiac sprue patients.

Authors:  Raffaella Di Cagno; Maria De Angelis; Salvatore Auricchio; Luigi Greco; Charmaine Clarke; Massimo De Vincenzi; Claudio Giovannini; Massimo D'Archivio; Francesca Landolfo; Giampaolo Parrilli; Fabio Minervini; Elke Arendt; Marco Gobbetti
Journal:  Appl Environ Microbiol       Date:  2004-02       Impact factor: 4.792

2.  Purification and Some Properties of a Membrane-Bound Aminopeptidase A from Streptococcus cremoris.

Authors:  F A Exterkate; G J de Veer
Journal:  Appl Environ Microbiol       Date:  1987-03       Impact factor: 4.792

3.  The activities of alanine aminopeptidase, leucine aminopeptidase, proline dipeptidase and prolyl dipeptidase in the mucosa of the small intestine. Investigations on normal children and patients with the malabsorption syndrome.

Authors:  J Grävinghoff; H J Hütter
Journal:  Eur J Pediatr       Date:  1977-12-30       Impact factor: 3.183

4.  Proteins of the kidney microvillar membrane. Aspartate aminopeptidase: purification by immunoadsorbent chromatography and properties of the detergent- and proteinase-solubilized forms.

Authors:  E M Danielsen; O Norén; H Sjöström; J Ingram; A J Kenny
Journal:  Biochem J       Date:  1980-09-01       Impact factor: 3.857

  4 in total

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