Literature DB >> 12446367

Heart defects and ocular anomalies in children with Down's syndrome.

N R Bromham1, J M Woodhouse, M Cregg, E Webb, W I Fraser.   

Abstract

AIMS: To investigate whether ocular anomalies are associated with congenital heart defects in children with Down's syndrome.
METHODS: 58 children with Down's syndrome were entered into a retrospective observational study. Children were assigned to heart defect groups based on medical records. Optometric tests had previously been carried out at the homes of the children.
RESULTS: A relation between congenital cardiac defects, myopia, and nystagmus was observed. Heart problems were not related to accommodative insufficiency, hyperopia, or strabismus.
CONCLUSION: In children with Down's syndrome heart defects were associated with both myopia and nystagmus.

Entities:  

Mesh:

Year:  2002        PMID: 12446367      PMCID: PMC1771425          DOI: 10.1136/bjo.86.12.1367

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  17 in total

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Authors:  R H Reeves; L L Baxter; J T Richtsmeier
Journal:  Trends Genet       Date:  2001-02       Impact factor: 11.639

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Review 5.  Collagens in ocular tissues.

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Journal:  Am J Med Genet       Date:  1983-02

7.  Refractive errors in young children with Down syndrome.

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