| Literature DB >> 12446008 |
M Laurà1, N A Gregson, Y Curmi, R A C Hughes.
Abstract
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine that exerts neurotrophic and myotrophic actions. We have investigated the effect of LIF in experimental autoimmune neuritis (EAN), an animal model of Guillain-Barré syndrome (GBS). Treatment with LIF at the onset of the disease showed a slight, but not significant, improvement in the clinical course but no effect on nerve histology.Entities:
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Year: 2002 PMID: 12446008 DOI: 10.1016/s0165-5728(02)00359-4
Source DB: PubMed Journal: J Neuroimmunol ISSN: 0165-5728 Impact factor: 3.478