Literature DB >> 12444709

Cytotoxic diarylheptanoids from the roots of Juglans mandshurica.

Kyung-Seon Lee1, Gao Li, Sung Hwan Kim, Chong-Soon Lee, Mi-Hee Woo, Seung-Ho Lee, Yurng-Dong Jhang, Jong-Keun Son.   

Abstract

A new (2) and three known diarylheptanoids (1, 3, and 4), along with one known sesquiterpenoid (5), were isolated from the roots of Juglans mandshurica, and their structures were elucidated on the basis of spectroscopic studies. Four of these compounds (2-5) exhibited moderate cytotoxicities against human colon carcinoma and human lung carcinoma cell lines with IC(50)'s ranging from 2 to 25 microg/mL.

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Year:  2002        PMID： 12444709     DOI： 10.1021/np0201063

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  The anti-tumor effect and biological activities of the extract JMM6 from the stem-barks of the Chinese Juglans mandshurica Maxim on human hepatoma cell line BEL-7402.

Authors:  Yongli Zhang; Yuqiang Cui; Jiayong Zhu; Hongzhi Li; Jianwen Mao; Xiaobao Jin; Xiangsheng Wang; Yifan Du; Jiazheng Lu
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-12-31

2.  Total synthesis and structural revision of engelhardione.

Authors:  Li Shen; Dianqing Sun
Journal:  Tetrahedron Lett       Date:  2011-08-31       Impact factor: 2.415

3.  Synthesis and evaluation of macrocyclic diarylether heptanoid natural products and their analogs.

Authors:  Vashti C Bryant; G D Kishore Kumar; Abijah M Nyong; Amarnath Natarajan
Journal:  Bioorg Med Chem Lett       Date:  2011-11-11       Impact factor: 2.823

4.  Diarylheptanoid analogues from the rhizomes of Zingiber officinale and their anti-tumour activity.

Authors:  Ting Li; Da-Bo Pan; Qian-Qian Pang; Mi Zhou; Xiao-Jun Yao; Xin-Sheng Yao; Hai-Bo Li; Yang Yu
Journal:  RSC Adv       Date:  2021-09-02       Impact factor: 4.036

5.  Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells.

Authors:  Ya-Qin Hou; Yao Yao; Yong-Li Bao; Zhen-Bo Song; Cheng Yang; Xiu-Li Gao; Wen-Jing Zhang; Lu-Guo Sun; Chun-Lei Yu; Yan-Xin Huang; Guan-Nan Wang; Yu-Xin Li
Journal:  Oxid Med Cell Longev       Date:  2015-11-22       Impact factor: 6.543

Review 6.  Juglans mandshurica Maxim.: A Review of Its Traditional Usages, Phytochemical Constituents, and Pharmacological Properties.

Authors:  Fei Luan; Ziyan Wang; Yan Yang; Yafei Ji; Haizhen Lv; Keqing Han; Daoheng Liu; Xiaofei Shang; Xirui He; Nan Zeng
Journal:  Front Pharmacol       Date:  2021-01-21       Impact factor: 5.810

7.  Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms.

Authors:  A F M Motiur Rahman; Wencui Yin; Adnan A Kadi; Yurngdong Jahng
Journal:  Molecules       Date:  2020-12-13       Impact factor: 4.411

Review 8.  Hedycaryol - Central Intermediates in Sesquiterpene Biosynthesis, Part II.

Authors:  Houchao Xu; Jeroen S Dickschat
Journal:  Chemistry       Date:  2022-03-21       Impact factor: 5.020

9.  Dietary Walnuts Protect Against Obesity-Driven Intestinal Stem Cell Decline and Tumorigenesis.

Authors:  Fangxia Guan; Tahmineh Tabrizian; Ardijana Novaj; Masako Nakanishi; Daniel W Rosenberg; Derek M Huffman
Journal:  Front Nutr       Date:  2018-05-31
  9 in total

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