| Literature DB >> 1244129 |
M Ackenheil, B Blatt, C Lampart.
Abstract
In a clinical study and with experiments in rats Clozapine showed a sedative effect, which diminished during the treatment, and indicated a development of tolerance. 5-HIAA in urine and CSF of patients was elevated after 10 days of treatment. 5-HT and 5-HIAA were elevated in the brains of rats in acute experiments as well as in chronic experiments.Entities:
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Year: 1975 PMID： 1244129
Source DB: PubMed Journal: Acta Vitaminol Enzymol ISSN： 0300-8924