Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The role of ovarian hormones in preserving cognition in aging.

Literature DB >> 12441027

The role of ovarian hormones in preserving cognition in aging.

Abstract

Hormone replacement therapy is now the standard of care for amelioration of the symptoms of menopause and prevention of osteoporosis. More recently, it has been appreciated that hormone replacement may also have beneficial effects on the brain. This review will contrast the biologic data showing that estrogen has significant neuroprotectant effects on the brain, with data from cross-sectional and epidemiologic studies of women showing that hormone replacement may have beneficial effects for cognition in aging. Together, studies suggest that the temporal pattern of hormone replacement may be critical for maintaining cognitive health in aging.

Entities: Disease Species

Mesh：

Substances：

Year: 2002 PMID： 12441027 DOI： 10.1007/s11920-002-0075-9

Source DB: PubMed Journal: Curr Psychiatry Rep ISSN： 1523-3812 Impact factor: 5.285

75 in total

Review 1. Estrogen actions in the central nervous system.

Authors: B S McEwen; S E Alves
Journal: Endocr Rev Date: 1999-06 Impact factor: 19.871

2. 1998 Curt P. Richter Award. The effect of hormone replacement therapy on cognitive function in elderly women.

Authors: E Hogervorst; M Boshuisen; W Riedel; C Willeken; J Jolles
Journal: Psychoneuroendocrinology Date: 1999-01 Impact factor: 4.905

3. Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway.

Authors: C B Wade; S Robinson; R A Shapiro; D M Dorsa
Journal: Endocrinology Date: 2001-06 Impact factor: 4.736

4. Steroid hormone action in the neuroendocrine system: when is the genome involved?

Authors: B S McEwen; L C Krey; V N Luine
Journal: Res Publ Assoc Res Nerv Ment Dis Date: 1978

5. Males and females use different distal cues in a virtual environment navigation task.

Authors: N J Sandstrom; J Kaufman; S A Huettel
Journal: Brain Res Cogn Brain Res Date: 1998-04

6. Estrogen increases the density of 5-hydroxytryptamine(2A) receptors in cerebral cortex and nucleus accumbens in the female rat.

Authors: B E Summer; G Fink
Journal: J Steroid Biochem Mol Biol Date: 1995-07 Impact factor: 4.292

1. Chronic estradiol replacement to aged female rats reduces anxiety-like and depression-like behavior and enhances cognitive performance.

Authors: Alicia A Walf; Jason J Paris; Cheryl A Frye
Journal: Psychoneuroendocrinology Date: 2009-02-11 Impact factor: 4.905

1 in total

The role of ovarian hormones in preserving cognition in aging.

Review 1. Estrogen actions in the central nervous system.

2. 1998 Curt P. Richter Award. The effect of hormone replacement therapy on cognitive function in elderly women.

3. Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway.

4. Steroid hormone action in the neuroendocrine system: when is the genome involved?

5. Males and females use different distal cues in a virtual environment navigation task.

6. Estrogen increases the density of 5-hydroxytryptamine(2A) receptors in cerebral cortex and nucleus accumbens in the female rat.

7. Neurologic function in the optimally healthy oldest old. Neuropsychological evaluation.

Review 8. Estrogen replacement therapy: current recommendations.

Review 9. Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore.

10. Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury.

1. Chronic estradiol replacement to aged female rats reduces anxiety-like and depression-like behavior and enhances cognitive performance.