Literature DB >> 12440887

Construction of hydrolytically-degradable thin films via layer-by-layer deposition of degradable polyelectrolytes.

Eduardo Vázquez1, David M Dewitt, Paula T Hammond, David M Lynn.   

Abstract

Hydrolytically degradable, multilayered films ranging from 10 to 100 nm have been constructed by the layer-by-layer deposition of degradable polycations and oppositely charged polyanions. Polycations play dual roles in these systems, serving as structural components of the film as well as transient elements designed to trigger release; polyanions serve as structural components and as entities to be released or delivered. The films erode in a controlled manner under physiological conditions and are suitable for the incorporation and subsequent controlled release of functional polyanions such as DNA.

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Year:  2002        PMID： 12440887     DOI： 10.1021/ja026405w

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  34 in total

1.  Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films.

Authors:  Kris C Wood; Helen F Chuang; Robert D Batten; David M Lynn; Paula T Hammond
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-26       Impact factor: 11.205

2.  Release of plasmid DNA from intravascular stents coated with ultrathin multilayered polyelectrolyte films.

Authors:  Christopher M Jewell; Jingtao Zhang; Nathaniel J Fredin; Matthew R Wolff; Timothy A Hacker; David M Lynn
Journal:  Biomacromolecules       Date:  2006-09       Impact factor: 6.988

3.  Structure/property relationships in erodible multilayered films: influence of polycation structure on erosion profiles and the release of anionic polyelectrolytes.

Authors:  Jingtao Zhang; Nathaniel J Fredin; John F Janz; Bin Sun; David M Lynn
Journal:  Langmuir       Date:  2006-01-03       Impact factor: 3.882

4.  Multifunctional polyelectrolyte multilayer films: combining mechanical resistance, biodegradability, and bioactivity.

Authors:  Aurore Schneider; Constant Vodouhê; Ludovic Richert; Gregory Francius; Erell Le Guen; Pierre Schaaf; Jean-Claude Voegel; Benoît Frisch; Catherine Picart
Journal:  Biomacromolecules       Date:  2007-01       Impact factor: 6.988

Review 5.  Biochemical applications of ultrathin films of enzymes, polyions and DNA.

Authors:  James F Rusling; Eli G Hvastkovs; Dominic O Hull; John B Schenkman
Journal:  Chem Commun (Camb)       Date:  2007-08-30       Impact factor: 6.222

6.  Electroactive controlled release thin films.

Authors:  Kris C Wood; Nicole S Zacharia; Daniel J Schmidt; Stefani N Wrightman; Brian J Andaya; Paula T Hammond
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-12       Impact factor: 11.205

7.  The effectiveness of the controlled release of gentamicin from polyelectrolyte multilayers in the treatment of Staphylococcus aureus infection in a rabbit bone model.

Authors:  Joshua S Moskowitz; Michael R Blaisse; Raymond E Samuel; Hu-Ping Hsu; Mitchel B Harris; Scott D Martin; Jean C Lee; Myron Spector; Paula T Hammond
Journal:  Biomaterials       Date:  2010-05-21       Impact factor: 12.479

8.  Targeted release of tobramycin from a pH-responsive grafted bilayer challenged with S. aureus.

Authors:  Hyun-Su Lee; Sana S Dastgheyb; Noreen J Hickok; David M Eckmann; Russell J Composto
Journal:  Biomacromolecules       Date:  2015-01-27       Impact factor: 6.988

9.  Ordered and kinetically discrete sequential protein release from biodegradable thin films.

Authors:  Bryan B Hsu; Kelsey S Jamieson; Samantha R Hagerman; Eggehard Holler; Julia Y Ljubimova; Paula T Hammond
Journal:  Angew Chem Int Ed Engl       Date:  2014-06-18       Impact factor: 15.336

10.  Multilayered Films Fabricated from Combinations of Degradable Polyamines: Tunable Erosion and Release of Anionic Polyelectrolytes.

Authors:  Jingtao Zhang; David M Lynn
Journal:  Macromolecules       Date:  2006-01-26       Impact factor: 5.985
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