| Literature DB >> 12440692 |
Rene E Harrison1, Sergio Grinstein.
Abstract
Phagocytosis is a critical host defense mechanism used by macrophages and neutrophils to clear invading pathogens. The complex sequence of events resulting in internalization and degradation of the pathogens is a coordinated process involving lipids, signaling proteins, and the cytoskeleton. Here, we examine the role of the microtubule cytoskeleton in supporting both the engulfment of pathogens and their elimination within phagolysosomes.Entities:
Mesh:
Year: 2002 PMID: 12440692 DOI: 10.1139/o02-142
Source DB: PubMed Journal: Biochem Cell Biol ISSN: 0829-8211 Impact factor: 3.626