Literature DB >> 12440614

The vacuum-assisted closure system for the treatment of deep sternal wound infections after cardiac surgery.

Tatjana M Fleck1, Michael Fleck, Reinhard Moidl, Martin Czerny, Rupert Koller, Pietro Giovanoli, Michael J Hiesmayer, Daniel Zimpfer, Ernst Wolner, Martin Grabenwoger.   

Abstract

BACKGROUND: The VAC system (vacuum-assisted wound closure) is a noninvasive active therapy to promote healing in difficult wounds that fail to respond to established treatment modalities. The system is based on the application of negative pressure by controlled suction to the wound surface. The method was introduced into clinical practice in 1996. Since then, numerous studies proved the effectiveness of the VAC System on microcirculation and the promotion of granulation tissue proliferation.
METHODS: Eleven patients (5 men, 6 women) with a median age of 64.4 years (range 50 to 78 years) with sternal wound infection after cardiac surgery (coronary artery bypass grafting = 5, aortic valve replacement = 5, ascending aortic replacement = 1) were fitted with the VAC system by the time of initial surgical debridement.
RESULTS: Complete healing was achieved in all patients. The VAC system was removed after a mean of 9.3 days (range 4 to 15 days), when systemic signs of infection resolved and quantitative cultures were negative. In 6 patients (54.5%), the VAC system was used as a bridge to reconstructive surgery with a pectoralis muscle flap, and in the remaining 5 patients (45.5%), primary wound closure could be achieved. Intensive care unit stay ranged from 1 to 4 days (median 1 day). Duration of hospital stay varied from 13 to 45 days (median 30 days). In-hospital mortality was 0%, and 30-day survival was 100%.
CONCLUSIONS: The VAC system can be considered as an effective and safe adjunct to conventional and established treatment modalities for the therapy of sternal wound infections after cardiac surgery.

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Year:  2002        PMID: 12440614     DOI: 10.1016/s0003-4975(02)03948-6

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  35 in total

1.  Acute mediastinal bleeding during vacuum-assisted closure.

Authors:  Roemer J Vos; Alaaddin Yilmaz; Uday Sonker; Geoffrey T L Kloppenburg
Journal:  Int Wound J       Date:  2012-05-28       Impact factor: 3.315

2.  The management of deep sternal wound infections using vacuum assisted closure (V.A.C.) therapy.

Authors:  Tatjana Fleck; Ronny Gustafsson; Keith Harding; Richard Ingemansson; Mitchell D Lirtzman; Herbert L Meites; Reinhard Moidl; Patricia Price; Andrew Ritchie; Jorge Salazar; Johan Sjögren; David H Song; Bauer E Sumpio; Boulos Toursarkissian; Ferdinand Waldenberger; Walter Wetzel-Roth
Journal:  Int Wound J       Date:  2006-12       Impact factor: 3.315

Review 3.  Topical negative pressure therapy: mechanisms and indications.

Authors:  Paul E Banwell; Melinda Musgrave
Journal:  Int Wound J       Date:  2004-06       Impact factor: 3.315

4.  Haemodynamic effects of -75 mmHg negative pressure therapy in a porcine sternotomy wound model.

Authors:  Arash Mokhtari; Ronny Gustafsson; Johan Sjögren; Johan Nilsson; Sandra Lindstedt; Malin Malmsjö; Richard Ingemansson
Journal:  Int Wound J       Date:  2009-02       Impact factor: 3.315

Review 5.  Topical negative pressure wound therapy: a review of its role and guidelines for its use in the management of acute wounds.

Authors:  Estas Bovill; Paul E Banwell; Luc Teot; Elof Eriksson; Colin Song; Jim Mahoney; Ronny Gustafsson; Raymund Horch; Anand Deva; Ian Whitworth
Journal:  Int Wound J       Date:  2008-09-19       Impact factor: 3.315

6.  Pressure transduction to the thoracic cavity during topical negative pressure therapy of a sternotomy wound.

Authors:  Christian Torbrand; Richard Ingemansson; Lotta Gustafsson; Per Paulsson; Malin Malmsjö
Journal:  Int Wound J       Date:  2008-09-19       Impact factor: 3.315

7.  Vacuum-assisted closure therapy for deep sternal wound infections: the impact of learning curve on survival and predictors for late mortality.

Authors:  Johan Sjögren; Arash Mokhtari; Ronny Gustafsson; Malin Malmsjö; Johan Nilsson; Richard Ingemansson
Journal:  Int Wound J       Date:  2008-06       Impact factor: 3.315

8.  Is post-sternotomy mediastinitis still devastating after the advent of negative-pressure wound therapy?

Authors:  Marisa De Feo; Alessandro Della Corte; Mariano Vicchio; Francesco Pirozzi; Gianantonio Nappi; Maurizio Cotrufo
Journal:  Tex Heart Inst J       Date:  2011

9.  Negative pressure wound therapy for the treatment of sternal wound infections after cardiac surgery.

Authors:  Tatjana Fleck; Michael Fleck
Journal:  Int Wound J       Date:  2012-09-03       Impact factor: 3.315

10.  Negative pressure wound therapy: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2006-07-01
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