OBJECTIVE: The purpose of this study was to determine whether size-discordant twin pairs have worse perinatal mortality and neonatal morbidity rates than nondiscordant pairs and whether the smaller twins of discordant pairs have worse perinatal outcomes than the larger twins. STUDY DESIGN: We conducted a population-based, retrospective analysis of linked birth certificates and fetal and infant death certificates for 9590 twin pairs who were born in the state of Washington from 1987 through 1999. The Cochran-Mantel-Haenszel test, Student t test, and McNemar test were among the tests used to assess statistical significance. RESULTS: Discordant twin pairs had higher rates of perinatal mortality, neonatal mortality, and 5-minute Apgar scores of <7, even after stratification by gestational age. Discordant pairs had lower pair weights at each gestational age and were more likely to include small-for-gestational-age infants. Compared with the larger twins, the smaller twins of discordant pairs had higher rates of perinatal mortality. CONCLUSION: Discordant pairs had worse perinatal outcomes within each gestational age category.
OBJECTIVE: The purpose of this study was to determine whether size-discordant twin pairs have worse perinatal mortality and neonatal morbidity rates than nondiscordant pairs and whether the smaller twins of discordant pairs have worse perinatal outcomes than the larger twins. STUDY DESIGN: We conducted a population-based, retrospective analysis of linked birth certificates and fetal and infant death certificates for 9590 twin pairs who were born in the state of Washington from 1987 through 1999. The Cochran-Mantel-Haenszel test, Student t test, and McNemar test were among the tests used to assess statistical significance. RESULTS: Discordant twin pairs had higher rates of perinatal mortality, neonatal mortality, and 5-minute Apgar scores of <7, even after stratification by gestational age. Discordant pairs had lower pair weights at each gestational age and were more likely to include small-for-gestational-age infants. Compared with the larger twins, the smaller twins of discordant pairs had higher rates of perinatal mortality. CONCLUSION: Discordant pairs had worse perinatal outcomes within each gestational age category.
Authors: Melissa M Amyx; Paul S Albert; Alaina M Bever; Stefanie N Hinkle; John Owen; William A Grobman; Roger B Newman; Edward K Chien; Robert E Gore-Langton; Germaine M Buck Louis; Katherine L Grantz Journal: Am J Obstet Gynecol Date: 2019-08-24 Impact factor: 8.661
Authors: Amira S Egic; Donka V Mojovic; Zagorka M Milovanovic; Aleksandar B Jurisic; Ljubomir P Srbinovic; Suzana P Krsmanovic; Natasa T Karadzov-Orlic Journal: Obstet Gynecol Int Date: 2014-07-07
Authors: Yoshie Yokoyama; Aline Jelenkovic; Reijo Sund; Joohon Sung; John L Hopper; Syuichi Ooki; Kauko Heikkilä; Sari Aaltonen; Adam D Tarnoki; David L Tarnoki; Gonneke Willemsen; Meike Bartels; Toos C E M van Beijsterveldt; Kimberly J Saudino; Tessa L Cutler; Tracy L Nelson; Keith E Whitfield; Jane Wardle; Clare H Llewellyn; Abigail Fisher; Mingguang He; Xiaohu Ding; Morten Bjerregaard-Andersen; Henning Beck-Nielsen; Morten Sodemann; Yun-Mi Song; Sarah Yang; Kayoung Lee; Hoe-Uk Jeong; Ariel Knafo-Noam; David Mankuta; Lior Abramson; S Alexandra Burt; Kelly L Klump; Juan R Ordoñana; Juan F Sánchez-Romera; Lucia Colodro-Conde; Jennifer R Harris; Ingunn Brandt; Thomas Sevenius Nilsen; Jeffrey M Craig; Richard Saffery; Fuling Ji; Feng Ning; Zengchang Pang; Lise Dubois; Michel Boivin; Mara Brendgen; Ginette Dionne; Frank Vitaro; Nicholas G Martin; Sarah E Medland; Grant W Montgomery; Patrik K E Magnusson; Nancy L Pedersen; Anna K Dahl Aslan; Per Tynelius; Claire M A Haworth; Robert Plomin; Esther Rebato; Richard J Rose; Jack H Goldberg; Finn Rasmussen; Yoon-Mi Hur; Thorkild I A Sørensen; Dorret I Boomsma; Jaakko Kaprio; Karri Silventoinen Journal: Twin Res Hum Genet Date: 2016-04 Impact factor: 1.587