Role of invasive electrophysiologic testing in the evaluation and management of adult patients with focal junctional tachycardia.

Focal junctional tachycardia (FJT) is characterized by a rapid often irregular narrow complex tachycardia with episodes of atrioventricular (AV) dissociation. This uncommon arrhythmia is most likely due to abnormal automaticity or triggered activity. The patients are often quite symptomatic and if left untreated may develop heart failure particularly if their tachycardia is incessant. In patients refractory to medical management, the role of radiofrequency ablation involves either (1) selective ablation of the tachycardia focus while preserving AV conduction or as a last resort (2) AV junction ablation followed by pacemaker implantation. The clinician should first assess whether ventriculoatrial (VA) conduction is present or absent during tachycardia. If present, radiofrequency ablation should be applied at the site of earliest retrograde atrial activation. In the absence of VA conduction and hence an atrial target site, sequential lesions should be applied in the posterior septum (slow pathway region) followed by lesions applied in midseptum and anteroseptum respectively if tachycardia persists. To further minimize the risk of AV nodal block, some authors delivered radiofrequency energy during atrial overdrive pacing to assess AV conduction during ablation. Others recommended mapping the perinodal region and applying radiofrequency ablation at the site where catheter manipulation resulted in tachycardia termination. Using this ablative approach, the risk of AV block is around 5-10%.