| Literature DB >> 12437030 |
Young Suk Won1, Hyo Jung Kwon, Goo Taeg Oh, Bang Hyun Kim, Chul Ho Lee, Yong Ho Park, Byung Hwa Hyun, Yang Kyu Choi.
Abstract
Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knockout mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.Entities:
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Year: 2002 PMID： 12437030 DOI： 10.1111/j.1348-0421.2002.tb02744.x
Source DB: PubMed Journal: Microbiol Immunol ISSN： 0385-5600 Impact factor: 1.955