| Literature DB >> 12435711 |
Thomas C Stoeckli1, Samantha MaWhinney, Jonathan Uy, Chengying Duan, Jing Lu, David Shugarts, Daniel R Kuritzkes.
Abstract
Mutations at reverse transcriptase codons 44, 118, 207, and 208 were significantly correlated with reduced zidovudine susceptibility in biologically cloned human immunodeficiency virus type 1 (HIV-1) isolates. Sequences from the Stanford HIV RT and Protease Sequence Database showed that these mutations were more common in HIV-1 isolates from patients treated with zidovudine and lamivudine than in patients not treated with these drugs.Entities:
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Year: 2002 PMID: 12435711 PMCID: PMC132743 DOI: 10.1128/AAC.46.12.4000-4003.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191