| Literature DB >> 12435710 |
Evangelos J Giamarellos-Bourboulis1, Lazaros Karnesis, Irene Galani, Helen Giamarellou.
Abstract
The time-kill effect of moxifloxacin on 20 genetically distinct isolates of Stenotrophomonas maltophilia resistant to trimethoprim-sulfamethoxazole was studied. The majority (80%) were killed by a concentration equivalent to four times the MIC; the MIC induced a transient decrease in bacterial counts at 4 h, followed by regrowth. No effect was detected in four isolates. These results merit further clinical consideration.Entities:
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Year: 2002 PMID: 12435710 PMCID: PMC132774 DOI: 10.1128/AAC.46.12.3997-3999.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191