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Literature DB >> 124355

Control of thymidine kinase synthesis in IHD vaccinia virus-infected thymidine kinase-deficient LM cells.

Abstract

The synthesis of vaccinia virus-induced thymidine kinase is normally arrested several hours after infection. In thymidine kinase-deficient LM cells infected with IHD strain of vaccinia virus, arrest occurs whether or not viral DNA synthesis is inhibited. With virus inactivated by UV irradiation, enzyme synthesis takes place, but arrest is abolished. It is suggested that an early viral genetic function is responsible for the cessation of thymidine kinase synthesis.

Entities: Disease

Mesh：

Substances：

Year: 1975 PMID： 124355 PMCID： PMC354651

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

12 in total

1. THE INDUCTION AND REPRESSION OF THYMIDINE KINASE IN THE POXVIRUS-INFECTED HELA CELL.

Authors: B R MCAUSLAN
Journal: Virology Date: 1963-11 Impact factor: 3.616

2. EFFECTS OF 5-FLUOROURACIL, ACTINOMYCIN D AND MITOMYCIN C ON THE INDUCTION OF THYMIDINE KINASE BY VACCINIA-INFECTED L-CELLS.

Authors: S KIT; L J PIEKARSKI; D R DUBBS
Journal: J Mol Biol Date: 1963-11 Impact factor: 5.469

3. DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE.

Authors: S KIT; D R DUBBS; L J PIEKARSKI; T C HSU
Journal: Exp Cell Res Date: 1963-08 Impact factor: 3.905

4. The purification fo four strains of poxvirus.

Authors: W K JOKLIK
Journal: Virology Date: 1962-09 Impact factor: 3.616

5. Induction of thymidine kinase by vaccinia-infected mouse fibroblasts.

Authors: S KIT; L J PIEKARSKI; D R DUBBS
Journal: J Mol Biol Date: 1963-01 Impact factor: 5.469

6. Electrophoresis of thymidine kinase activity synthesized by cells transformed by herpes simplex virus.

Authors: W Munyon; R Buchsbaum; E Paoletti; J Mann; E Kraiselburd; D Davis
Journal: Virology Date: 1972-09 Impact factor: 3.616

7. Vaccinia mRNA synthesis under conditions which prevent uncoating.

Authors: B Woodson
Journal: Biochem Biophys Res Commun Date: 1967-04-20 Impact factor: 3.575

Review 8. Viral-induced enzymes and the problem of viral oncogenesis.

Authors: S Kit
Journal: Adv Cancer Res Date: 1968 Impact factor: 6.242

9. Studies on "early" enzymes in HeLa cells infected with vaccinia virus.

Authors: C Jungwirth; W K Joklik
Journal: Virology Date: 1965-09 Impact factor: 3.616

10. Induction of cytoplasmic ribonucleic acid (RNA) synthesis in vaccinia-infected LM cells during inhibition of protein synthesis.

Authors: W H Munyon; S Kit
Journal: Virology Date: 1966-06 Impact factor: 3.616

5 in total

Control of thymidine kinase synthesis in IHD vaccinia virus-infected thymidine kinase-deficient LM cells.

1. THE INDUCTION AND REPRESSION OF THYMIDINE KINASE IN THE POXVIRUS-INFECTED HELA CELL.

2. EFFECTS OF 5-FLUOROURACIL, ACTINOMYCIN D AND MITOMYCIN C ON THE INDUCTION OF THYMIDINE KINASE BY VACCINIA-INFECTED L-CELLS.

3. DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE.

4. The purification fo four strains of poxvirus.

5. Induction of thymidine kinase by vaccinia-infected mouse fibroblasts.

6. Electrophoresis of thymidine kinase activity synthesized by cells transformed by herpes simplex virus.

7. Vaccinia mRNA synthesis under conditions which prevent uncoating.

Review 8. Viral-induced enzymes and the problem of viral oncogenesis.

9. Studies on "early" enzymes in HeLa cells infected with vaccinia virus.

10. Induction of cytoplasmic ribonucleic acid (RNA) synthesis in vaccinia-infected LM cells during inhibition of protein synthesis.

1. Inhibition of vaccinia virus growth by zinc ions: effects on early RNA and thymidine kinase synthesis.

2. Uncoating of vaccinia virus.

3. Control of expression of the vaccinia virus thymidine kinase gene.

4. Vaccinia virus induces ribonucleotide reductase in primate cells.

5. Vaccinia virus produces late mRNAs by discontinuous synthesis.