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Literature DB >> 124351

The interaction of ATP-analogues possessing a blocked gamma-phosphate group with the sodium pump in human red cells.

Abstract

1. The (Na++K+)-ATPase of red cell membranes is unable to hydrolyse ATP-analogues in which the oxygen atom linking the beta- and gamma-phosphate groups is replaced by a minusCH2minus or minusNH-bridge. 2. In resealed ghosts both these ATP-analogues support K:K exchange but not Na:K exchange. ATP supports both modes of operation of the sodium pump, whereas neither occurs without any nucleotide. 3. These results support the hypothesis that ATP is needed as a cofactor for K:K exchange to occur, and make it extremely unlikely that phosphorylation from ATP is involved.

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Year: 1975 PMID： 124351 PMCID： PMC1330832 DOI： 10.1113/jphysiol.1975.sp010822

Source DB: PubMed Journal: J Physiol ISSN： 0022-3751 Impact factor: 5.182

13 in total

1. The catalytic effect of molybdate on the hydrolysis of organic phosphate bonds.

Authors: H WEIL-MALHERBE; R H GREEN
Journal: Biochem J Date: 1951-08 Impact factor: 3.857

Review 2. Some "partial reactions" of the sodium pump.

Authors: I M Glynn; J F Hoffman; V L Lew
Journal: Philos Trans R Soc Lond B Biol Sci Date: 1971-08-20 Impact factor: 6.237

3. Purification and characterization of (Na+ plus K+ )-ATPase. IV. Estimation of the purity and of the molecular weight and polypeptide content per enzyme unit in preparations from the outer medulla of rabbit kidney.

Authors: P L Jorgensen
Journal: Biochim Biophys Acta Date: 1974-07-12

4. Ouabain binding to (Na+ plus K+)-ATPase. Effects of nucleotide analogues and ethacrynic acid.

Authors: T Tobin; T Akera; C Y Lee; T M Brody
Journal: Biochim Biophys Acta Date: 1974-04-12

5. Binding of adenosine triphosphate to sodium and potassium ion-stimulated adenosine triphosphatase.

Authors: C Hegyvary; R L Post
Journal: J Biol Chem Date: 1971-09-10 Impact factor: 5.157

6. The uncoupled extrusion of Na+ through the Na+ pump.

Authors: V L Lew; M A Hardy; J C Ellory
Journal: Biochim Biophys Acta Date: 1973-10-11

7. Nucleotide requirements for sodium-sodium exchange catalysed by the sodium pump in human red cells.

Authors: I M Glynn; J F Hoffman
Journal: J Physiol Date: 1971-10 Impact factor: 5.182

8. Interaction of P--N--P and P--C--P analogs of adenosine triphosphate with heavy meromyosin, myosin, and actomyosin.

Authors: R G Yount; D Ojala; D Babcock
Journal: Biochemistry Date: 1971-06-22 Impact factor: 3.162

9. Potassium: potassium exchange catalysed by the sodium pump in human red cells.

Authors: T J Simons
Journal: J Physiol Date: 1974-02 Impact factor: 5.182

10. The stoicheiometry of the sodium pump.

Authors: P J Garrahan; I M Glynn
Journal: J Physiol Date: 1967-09 Impact factor: 5.182

18 in total

1. Na+/K+-pump ligands modulate gating of palytoxin-induced ion channels.

Authors: Pablo Artigas; David C Gadsby
Journal: Proc Natl Acad Sci U S A Date: 2002-12-23 Impact factor: 11.205

2. Reconstitution and purification by "transport specificity fractionation" of an ATP-dependent calcium transport component from synaptosome-derived vesicles.

Authors: D Papazian; H Rahamimoff; S M Goldin
Journal: Proc Natl Acad Sci U S A Date: 1979-08 Impact factor: 11.205

3. ATP hydrolysis associated with an uncoupled sodium flux through the sodium pump: evidence for allosteric effects of intracellular ATP and extracellular sodium.

Authors: I M Glynn; S J Karlish
Journal: J Physiol Date: 1976-04 Impact factor: 5.182

Review 4. Review. Peering into an ATPase ion pump with single-channel recordings.

Authors: David C Gadsby; Ayako Takeuchi; Pablo Artigas; Nicolás Reyes
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2009-01-27 Impact factor: 6.237

Review 5. Electrogenic properties of the Na,K pump.

Authors: H J Apell
Journal: J Membr Biol Date: 1989-09 Impact factor: 1.843

6. Potassium-potassium exchange as part of the over-all reaction mechanism of the sodium pump of the human red blood cell.

Authors: J R Sachs
Journal: J Physiol Date: 1986-05 Impact factor: 5.182

7. Solubilized alpha beta Na,K-ATPase remains protomeric during turnover yet shows apparent negative cooperativity toward ATP.

Authors: D G Ward; J D Cavieres
Journal: Proc Natl Acad Sci U S A Date: 1993-06-01 Impact factor: 11.205